Surgical Treatment of Rare Multiple Cardiac Myxomas: A 13-Year Clinical Experience at a Single Institution.
- 1The First Affiliated Hospital of Bengbu Medical University Department of Cardiac Surgery Bengbu Anhui People's Republic of China Department of Cardiac Surgery, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People's Republic of China.
- 2Bengbu Medical University Graduate School of Bengbu Medical University Bengbu Anhui People's Republic of China Graduate School of Bengbu Medical University, Bengbu Medical University, Bengbu, Anhui, People's Republic of China.
Abstract
Introduction
Cardiac myxoma (CM) is the most common primary cardiac tumor. Multiple CMs are rare and can lead to heart failure and arterial embolism. This study aimed to explore clinical characteristics, surgical treatment experience, and follow-up strategies for multiple CMs.Methods
A retrospective analysis was conducted on eight patients with multiple CMs who underwent surgical treatment. Clinical characteristics were analyzed by extracting relevant clinical data, electrocardiography and echocardiography findings, surgical treatment details, and postoperative follow-up information. All patients had undergone cardiopulmonary bypass surgery. Pathological analysis was performed on all tumors, and postoperative cardiac ultrasound follow-up was also conducted.Results
Multiple CMs were uncommon, representing only 5.9% of all cases. Among 136 patients with cardiac tumors admitted during the same period, only eight had multiple CMs. All patients with multiple CMs underwent complete tumor resection. The size of the resected tumors was approximately 5-80 (39.3 ± 20.3) mm. The follow-up period ranged from one to nine years. The recurrence rate was 37.5% (3/8), and all recurrent cases underwent reoperation for tumor resection. There were no perioperative deaths, and overall surgical outcomes were satisfactory.Conclusion
Our study reveals that surgery is the best strategy for multiple CMs. The tumor should be completely resected, and color Doppler echocardiography is recommended every six months postoperatively to detect tumor recurrence. Those cases of multiple myxomas have had high recurrence rate after resection (37.5%) but were submitted successfully to a new resection. Timely surgical resection provides favorable outcomes for patients with multiple or recurrent CMs.
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BibTeX
@article{diao2026surgical,
title = {{Surgical Treatment of Rare Multiple Cardiac Myxomas: A 13-Year Clinical Experience at a Single Institution.}},
author = {Wenjie Diao and Shengqiang Zhang and Shaofeng Yang and Yu Shi and Chongwen Shen and Chão Cai and Shicheng Xie and Chao Shi and Ge Liu},
journal = {Brazilian journal of cardiovascular surgery},
year = {2026},
month = jul,
doi = {10.21470/1678-9741-2025-0145},
url = {https://europepmc.org/article/MED/42899559},
note = {CC BY},
}
RIS
TY - JOUR
TI - Surgical Treatment of Rare Multiple Cardiac Myxomas: A 13-Year Clinical Experience at a Single Institution.
AU - Wenjie Diao
AU - Shengqiang Zhang
AU - Shaofeng Yang
AU - Yu Shi
AU - Chongwen Shen
AU - Chão Cai
AU - Shicheng Xie
AU - Chao Shi
AU - Ge Liu
PY - 2026
DA - 2026/07/01
JO - Brazilian journal of cardiovascular surgery
DO - 10.21470/1678-9741-2025-0145
UR - https://europepmc.org/article/MED/42899559
AB - Introduction Cardiac myxoma (CM) is the most common primary cardiac tumor. Multiple CMs are rare and can lead to heart failure and arterial embolism. This study aimed to explore clinical characteristics, surgical treatment experience, and follow-up strategies for multiple CMs.Methods A retrospective analysis was conducted on eight patients with multiple CMs who underwent surgical treatment. Clinical characteristics were analyzed by extracting relevant clinical data, electrocardiography and echocardiography findings, surgical treatment details, and postoperative follow-up information. All patients had undergone cardiopulmonary bypass surgery. Pathological analysis was performed on all tumors, and postoperative cardiac ultrasound follow-up was also conducted.Results Multiple CMs were uncommon, representing only 5.9% of all cases. Among 136 patients with cardiac tumors admitted during the same period, only eight had multiple CMs. All patients with multiple CMs underwent complete tumor resection. The size of the resected tumors was approximately 5-80 (39.3 ± 20.3) mm. The follow-up period ranged from one to nine years. The recurrence rate was 37.5% (3/8), and all recurrent cases underwent reoperation for tumor resection. There were no perioperative deaths, and overall surgical outcomes were satisfactory.Conclusion Our study reveals that surgery is the best strategy for multiple CMs. The tumor should be completely resected, and color Doppler echocardiography is recommended every six months postoperatively to detect tumor recurrence. Those cases of multiple myxomas have had high recurrence rate after resection (37.5%) but were submitted successfully to a new resection. Timely surgical resection provides favorable outcomes for patients with multiple or recurrent CMs.
SN - 0102-7638
SN - 1678-9741
ER -