Influence of Perioperative Variables on Surgical Site Infection in Patients With Frailty and Prefrailty Undergoing Coronary Artery Bypass Grafting: Retrospective Multicenter Study
Abstract
BackgroundSurgical site infection (SSI) in patients with frailty undergoing myocardial revascularization is a major clinical challenge, and there is a gap in the literature related to this topic. ObjectiveThis study aimed to identify perioperative variables associated with SSI in patients with frailty and prefrailty undergoing coronary artery bypass grafting within 30 days of the procedure. MethodsThis retrospective observational study included 467 patients with frailty or prefrailty aged 60 years and older who underwent coronary artery bypass grafting in 6 Brazilian centers between January 2018 and December 2024. Frailty was defined using the Fried criteria. SSI was defined as a wound with exposed tissue with positive culture requiring antibiotic treatment. Univariate and multivariate analyses were carried out. ResultsThe rate of SSI was 5.6% (26/467). The New York Heart Association classification (PPPPPPPPPPPP ConclusionsThe CCI and the use of CPB were independently associated with SSI.
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BibTeX
@article{guerrieri2026influence,
title = {{Influence of Perioperative Variables on Surgical Site Infection in Patients With Frailty and Prefrailty Undergoing Coronary Artery Bypass Grafting: Retrospective Multicenter Study}},
author = {Mauricio Guerrieri and Omar Mejia and Bianca Meneghini and Natali Rodrigues and William Burato and Maisa Barros and Daniel Wernsbach and Lucas Bartelega and Alexandre Hueb and Fabio Jatene},
journal = {JMIR Cardio},
year = {2026},
month = oct,
doi = {10.2196/79408},
url = {https://doi.org/10.2196/79408},
note = {CC BY},
}
RIS
TY - JOUR
TI - Influence of Perioperative Variables on Surgical Site Infection in Patients With Frailty and Prefrailty Undergoing Coronary Artery Bypass Grafting: Retrospective Multicenter Study
AU - Mauricio Guerrieri
AU - Omar Mejia
AU - Bianca Meneghini
AU - Natali Rodrigues
AU - William Burato
AU - Maisa Barros
AU - Daniel Wernsbach
AU - Lucas Bartelega
AU - Alexandre Hueb
AU - Fabio Jatene
PY - 2026
DA - 2026/10/23
JO - JMIR Cardio
DO - 10.2196/79408
UR - https://doi.org/10.2196/79408
AB - BackgroundSurgical site infection (SSI) in patients with frailty undergoing myocardial revascularization is a major clinical challenge, and there is a gap in the literature related to this topic. ObjectiveThis study aimed to identify perioperative variables associated with SSI in patients with frailty and prefrailty undergoing coronary artery bypass grafting within 30 days of the procedure. MethodsThis retrospective observational study included 467 patients with frailty or prefrailty aged 60 years and older who underwent coronary artery bypass grafting in 6 Brazilian centers between January 2018 and December 2024. Frailty was defined using the Fried criteria. SSI was defined as a wound with exposed tissue with positive culture requiring antibiotic treatment. Univariate and multivariate analyses were carried out. ResultsThe rate of SSI was 5.6% (26/467). The New York Heart Association classification (PPPPPPPPPPPP ConclusionsThe CCI and the use of CPB were independently associated with SSI.
SN - 2561-1011
ER -