Peer-reviewedCC BY-NC-NDOrganometallics
Visible-Light-Driven C-F Bond Cleavage in Perfluoroalkyl Carboxylic Acids: Readily Accessible Ruthenium-Bipyridine Complexes as Effective Catalysts.
- 1Department of Chemistry, Marquette University, Milwaukee, Wisconsin 53201, United States.
Abstract
Herein, we report the reaction discovery and mechanistic studies of a visible-light-driven defluorination reaction of perfluoroalkyl carboxylic acids (PFCAs), a major class of perfluoroalkyl substances (PFAS) widely present in the environment that pose significant health and environmental concerns. The developed reaction employs 1-5 mol % of commercially available or readily accessible Ru-bipyridine complexes as the catalyst and achieves efficient C-F bond cleavage for C2-C8 PFCAs, perfluorinated dicarboxylic acids, and partially fluorinated carboxylic acids. Mechanistic studies suggest that the reaction proceeds via an inner-sphere pathway involving light-driven steps such as solvent-promoted ligand dissociation and Ru-O homolysis.
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BibTeX
@article{wickramaarachchi2026visiblelightdriven,
title = {{Visible-Light-Driven C-F Bond Cleavage in Perfluoroalkyl Carboxylic Acids: Readily Accessible Ruthenium-Bipyridine Complexes as Effective Catalysts.}},
author = {Ashan S Wickramaarachchi and Ishan D Jayampathi and Maggie M Larson and Alexander N Erickson and Dian Wang},
journal = {Organometallics},
year = {2026},
month = oct,
doi = {10.1021/acs.organomet.6c00279},
url = {https://europepmc.org/article/MED/42953798},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Visible-Light-Driven C-F Bond Cleavage in Perfluoroalkyl Carboxylic Acids: Readily Accessible Ruthenium-Bipyridine Complexes as Effective Catalysts.
AU - Ashan S Wickramaarachchi
AU - Ishan D Jayampathi
AU - Maggie M Larson
AU - Alexander N Erickson
AU - Dian Wang
PY - 2026
DA - 2026/10/14
JO - Organometallics
DO - 10.1021/acs.organomet.6c00279
UR - https://europepmc.org/article/MED/42953798
AB - Herein, we report the reaction discovery and mechanistic studies of a visible-light-driven defluorination reaction of perfluoroalkyl carboxylic acids (PFCAs), a major class of perfluoroalkyl substances (PFAS) widely present in the environment that pose significant health and environmental concerns. The developed reaction employs 1-5 mol % of commercially available or readily accessible Ru-bipyridine complexes as the catalyst and achieves efficient C-F bond cleavage for C2-C8 PFCAs, perfluorinated dicarboxylic acids, and partially fluorinated carboxylic acids. Mechanistic studies suggest that the reaction proceeds via an inner-sphere pathway involving light-driven steps such as solvent-promoted ligand dissociation and Ru-O homolysis.
SN - 0276-7333
SN - 1520-6041
ER -