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Peer-reviewedCC BY 4.0Frontiers in Psychiatry

Intergenerational burden: deconstructing the dual impact of familial suicide in a specialized bipolar clinic, from clinical risk to internalized stigma

4 affiliations
  1. 1Department of Psychiatry, Kocaeli University Research and Application Hospital
  2. 2Department of Psychiatry, Kocaeli City Hospital
  3. 3Department of Psychiatry, Derince Training and Research Hospital
  4. 4Department of Psychiatry, Eyüpsultan State Hospital

Abstract

Background: This study aimed to assess the level of internalized stigma in individuals with bipolar disorder (BD) during the euthymic phase and to examine its individual, familial, and clinical predictors.

Method: Ninety-seven euthymic participants with BD, diagnosed according to DSM-5 criteria, were administered the Internalized Stigma of Mental Illness Scale (ISMI), Resilience Scale for Adults (RSA), and Rosenberg Self-Esteem Scale (RSES).

Results: High levels of internalized stigma (ISMI mean ≥ 2.5) were found in 13.4% of participants. Multiple linear regression analysis showed that higher resilience (β = –0.39, p <.001) and higher educational attainment (β = –0.18, p = .029) were associated with lower internalized stigma, whereas a family history of death by suicide was associated with higher stigma (β = 0.20, p = .019). A greater number of mood episodes showed a borderline association with higher stigma (β = 0.18, p = .050). The overall model explained 52% of the variance in stigma scores.

Limitations: The cross-sectional design and relatively small sample size are the primary limitations.

Conclusions: Internalized stigma in BD was associated with a combination of individual, familial, and educational factors. The independent association of a family history of suicide underscores the importance of a systematic evaluation of such a family history in a clinical interview, suggesting that strengthening resilience and health literacy may represent vital targets for intervention.

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BibTeX
@article{kocaayan2026intergenerational,
  title = {{Intergenerational burden: deconstructing the dual impact of familial suicide in a specialized bipolar clinic, from clinical risk to internalized stigma}},
  author = {Fatma Seher Kocaayan and Ezgi Şişman and Havva Atasoy Kaplan and İlay Dalkıran and Hanife Yılmaz Abaylı and Aslıhan Polat},
  journal = {Frontiers in Psychiatry},
  year = {2026},
  month = oct,
  doi = {10.3389/fpsyt.2026.1931254},
  url = {https://www.frontiersin.org/articles/10.3389/fpsyt.2026.1931254/full},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Intergenerational burden: deconstructing the dual impact of familial suicide in a specialized bipolar clinic, from clinical risk to internalized stigma
AU  - Fatma Seher Kocaayan
AU  - Ezgi Şişman
AU  - Havva Atasoy Kaplan
AU  - İlay Dalkıran
AU  - Hanife Yılmaz Abaylı
AU  - Aslıhan Polat
PY  - 2026
DA  - 2026/10/20
JO  - Frontiers in Psychiatry
DO  - 10.3389/fpsyt.2026.1931254
UR  - https://www.frontiersin.org/articles/10.3389/fpsyt.2026.1931254/full
AB  - Background: This study aimed to assess the level of internalized stigma in individuals with bipolar disorder (BD) during the euthymic phase and to examine its individual, familial, and clinical predictors.  Method: Ninety-seven euthymic participants with BD, diagnosed according to DSM-5 criteria, were administered the Internalized Stigma of Mental Illness Scale (ISMI), Resilience Scale for Adults (RSA), and Rosenberg Self-Esteem Scale (RSES).  Results: High levels of internalized stigma (ISMI mean ≥ 2.5) were found in 13.4% of participants. Multiple linear regression analysis showed that higher resilience (β = –0.39, p <.001) and higher educational attainment (β = –0.18, p = .029) were associated with lower internalized stigma, whereas a family history of death by suicide was associated with higher stigma (β = 0.20, p = .019). A greater number of mood episodes showed a borderline association with higher stigma (β = 0.18, p = .050). The overall model explained 52% of the variance in stigma scores.  Limitations: The cross-sectional design and relatively small sample size are the primary limitations.  Conclusions: Internalized stigma in BD was associated with a combination of individual, familial, and educational factors. The independent association of a family history of suicide underscores the importance of a systematic evaluation of such a family history in a clinical interview, suggesting that strengthening resilience and health literacy may represent vital targets for intervention.
SN  - 1664-0640
ER  -