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Peer-reviewedCC BY 4.0Emerging Infectious Diseases

Importation-Driven Measles Resurgence and the Fragility of Elimination, Japan, 2024–2026

Abstract

As measles elimination unravels across the Americas, Europe, and the Western Pacific, Japan is experiencing a resurgence of measles; the World Health Organization had verified elimination of measles in Japan in 2015. By epidemiologic week 20 of 2026, a total of 498 cases had been reported, exceeding every full-year total since 2020. Median case-patient age has fallen to 26 years, shifting the burden from a generation who received single-dose measles vaccinations to younger cohorts caught between successive vaccination-policy transitions. Among case-patients with a documented 2-dose vaccination history, more than half experienced modified measles, an attenuated, easily missed illness that delays diagnosis and isolation. As mass gatherings concentrate global travel, Japan has become a sentinel for the fragility of measles elimination, including in countries that consider elimination status secure. Surveillance shows importation-driven resurgence; the shift in genotype profile from D8 to B3 predominance back to D8 enabled tracking of source countries.

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BibTeX
@article{yuji2026importationdriven,
  title = {{Importation-Driven Measles Resurgence and the Fragility of Elimination, Japan, 2024–2026}},
  author = {Koichiro Yuji and Wakako Yuji and Eisuke Adachi},
  journal = {Emerging Infectious Diseases},
  year = {2026},
  month = oct,
  doi = {10.3201/eid3211.261187},
  url = {https://doi.org/10.3201/eid3211.261187},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Importation-Driven Measles Resurgence and the Fragility of Elimination, Japan, 2024–2026
AU  - Koichiro Yuji
AU  - Wakako Yuji
AU  - Eisuke Adachi
PY  - 2026
DA  - 2026/10/30
JO  - Emerging Infectious Diseases
DO  - 10.3201/eid3211.261187
UR  - https://doi.org/10.3201/eid3211.261187
AB  - As measles elimination unravels across the Americas, Europe, and the Western Pacific, Japan is experiencing a resurgence of measles; the World Health Organization had verified elimination of measles in Japan in 2015. By epidemiologic week 20 of 2026, a total of 498 cases had been reported, exceeding every full-year total since 2020. Median case-patient age has fallen to 26 years, shifting the burden from a generation who received single-dose measles vaccinations to younger cohorts caught between successive vaccination-policy transitions. Among case-patients with a documented 2-dose vaccination history, more than half experienced modified measles, an attenuated, easily missed illness that delays diagnosis and isolation. As mass gatherings concentrate global travel, Japan has become a sentinel for the fragility of measles elimination, including in countries that consider elimination status secure. Surveillance shows importation-driven resurgence; the shift in genotype profile from D8 to B3 predominance back to D8 enabled tracking of source countries.
SN  - 1080-6040
SN  - 1080-6059
ER  -