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Peer-reviewedCC BYScientific Reports

Nonmedical drug use and suicidal ideation among adolescents in the Republic of Korea: a population-based study

  1. 1Department of Biomedical Science and Multidisciplinary Genome Institute, Hallym University
  2. 2School of Nursing, Research Institute of Nursing Science, Hallym University

Abstract

Nonmedical drug use (NMU) among adolescents is an emerging public-health concern; however, population-based evidence on its association with suicidal ideation in the Republic of Korea remains limited. Using pooled data from the 2022–2024 Korea Youth Risk Behavior Survey (N = 158,829), we examined factors associated with lifetime NMU and its cross-sectional association with suicidal ideation during the previous 12 months using complex-samples logistic regression. A total of 2348 adolescents reported lifetime NMU (weighted prevalence, 1.6%; 95% CI 1.5–1.6%). Suicidal ideation was reported by 46.1% of adolescents with NMU and 12.8% of those without NMU. In fully adjusted models, NMU was associated with high perceived stress, higher GAD-7 total score, depressive symptoms, sexual intercourse experience, and alcohol blackout in the previous 30 days. After sequential adjustment for psychological distress and co-occurring health-risk behaviors, NMU remained associated with suicidal ideation (adjusted odds ratio = 2.55, 95% CI 2.27–2.87; P < 0.001). In the fully adjusted model, the adjusted predicted probability of suicidal ideation was 23.2% (95% CI 21.7%–24.7%) among adolescents with NMU and 13.1% (95% CI 12.9%–13.3%) among those without NMU, corresponding to an absolute difference of 10.1% points (95% CI 8.6–11.7). These findings indicate that lifetime NMU is associated with psychological distress, co-occurring health-risk behaviors, and suicidal ideation at the population level. Given the cross-sectional design and differing reference periods of the measures, the results should be interpreted as associations rather than evidence of temporal or causal relationships.

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BibTeX
@article{park2026nonmedical,
  title = {{Nonmedical drug use and suicidal ideation among adolescents in the Republic of Korea: a population-based study}},
  author = {Jong Kook Park and Jungmin Lee and Su Jung Lee},
  journal = {Scientific Reports},
  year = {2026},
  month = jul,
  doi = {10.1038/s41598-026-62341-5},
  url = {https://doi.org/10.1038/s41598-026-62341-5},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Nonmedical drug use and suicidal ideation among adolescents in the Republic of Korea: a population-based study
AU  - Jong Kook Park
AU  - Jungmin Lee
AU  - Su Jung Lee
PY  - 2026
DA  - 2026/07/01
JO  - Scientific Reports
DO  - 10.1038/s41598-026-62341-5
UR  - https://doi.org/10.1038/s41598-026-62341-5
AB  - Nonmedical drug use (NMU) among adolescents is an emerging public-health concern; however, population-based evidence on its association with suicidal ideation in the Republic of Korea remains limited. Using pooled data from the 2022–2024 Korea Youth Risk Behavior Survey (N = 158,829), we examined factors associated with lifetime NMU and its cross-sectional association with suicidal ideation during the previous 12 months using complex-samples logistic regression. A total of 2348 adolescents reported lifetime NMU (weighted prevalence, 1.6%; 95% CI 1.5–1.6%). Suicidal ideation was reported by 46.1% of adolescents with NMU and 12.8% of those without NMU. In fully adjusted models, NMU was associated with high perceived stress, higher GAD-7 total score, depressive symptoms, sexual intercourse experience, and alcohol blackout in the previous 30 days. After sequential adjustment for psychological distress and co-occurring health-risk behaviors, NMU remained associated with suicidal ideation (adjusted odds ratio = 2.55, 95% CI 2.27–2.87; P < 0.001). In the fully adjusted model, the adjusted predicted probability of suicidal ideation was 23.2% (95% CI 21.7%–24.7%) among adolescents with NMU and 13.1% (95% CI 12.9%–13.3%) among those without NMU, corresponding to an absolute difference of 10.1% points (95% CI 8.6–11.7). These findings indicate that lifetime NMU is associated with psychological distress, co-occurring health-risk behaviors, and suicidal ideation at the population level. Given the cross-sectional design and differing reference periods of the measures, the results should be interpreted as associations rather than evidence of temporal or causal relationships.
SN  - 2045-2322
ER  -