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Peer-reviewedCC BY-NC-NDInternal Medicine

Pneumatosis Cystoides Intestinalis Secondary to Antibiotic Therapy for Pulmonary Mycobacterium avium Complex Infection: A Case Report and Review of the Literature

Abstract

Pneumatosis cystoides intestinalis (PCI) is characterized by the presence of gas in the gastrointestinal wall. It is rarely observed in patients with pulmonary Mycobacterium avium complex (MAC) infection, although the exact mechanisms are unclear. We, herein, present a case of PCI potentially associated with long-term antibiotic therapy for pulmonary MAC infection. An 83-year-old woman developed PCI after 3 years of antibiotic therapy for a pulmonary MAC infection, with subsequent improvement following the discontinuation of antibiotics. Based on the clinical course, we suggest that clinicians consider the development of PCI, especially in patients receiving long-term antibiotic therapy for pulmonary MAC infection.

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BibTeX
@article{nakashima2026pneumatosis,
  title = {{Pneumatosis Cystoides Intestinalis Secondary to Antibiotic Therapy for Pulmonary Mycobacterium avium Complex Infection: A Case Report and Review of the Literature}},
  author = {Koki Nakashima and Hiroki Matsukawa and Toshiko Kakiuchi and Koji Yamaoka and Yasushi Hosokawa and Yuko Waseda},
  journal = {Internal Medicine},
  year = {2026},
  month = sep,
  doi = {10.2169/internalmedicine.6742-25},
  url = {https://www.jstage.jst.go.jp/article/internalmedicine/65/17/65_6742-25/_article},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Pneumatosis Cystoides Intestinalis Secondary to Antibiotic Therapy for Pulmonary Mycobacterium avium Complex Infection: A Case Report and Review of the Literature
AU  - Koki Nakashima
AU  - Hiroki Matsukawa
AU  - Toshiko Kakiuchi
AU  - Koji Yamaoka
AU  - Yasushi Hosokawa
AU  - Yuko Waseda
PY  - 2026
DA  - 2026/09/01
JO  - Internal Medicine
DO  - 10.2169/internalmedicine.6742-25
UR  - https://www.jstage.jst.go.jp/article/internalmedicine/65/17/65_6742-25/_article
AB  - Pneumatosis cystoides intestinalis (PCI) is characterized by the presence of gas in the gastrointestinal wall. It is rarely observed in patients with pulmonary Mycobacterium avium complex (MAC) infection, although the exact mechanisms are unclear. We, herein, present a case of PCI potentially associated with long-term antibiotic therapy for pulmonary MAC infection. An 83-year-old woman developed PCI after 3 years of antibiotic therapy for a pulmonary MAC infection, with subsequent improvement following the discontinuation of antibiotics. Based on the clinical course, we suggest that clinicians consider the development of PCI, especially in patients receiving long-term antibiotic therapy for pulmonary MAC infection.
SN  - 1349-7235
SN  - 0918-2918
ER  -