A scientometric study on research trends and characteristics of lymph node metastasis in oral cancer.
- 1Department of Oral and Maxillofacial Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
- 2Department of Oral and Maxillofacial-Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
- 3College of Stomatology, Shanghai Jiao Tong University, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.
Abstract
Background/purpose
Cervical lymph node metastasis (LNM) is the most critical prognostic factor in oral cancer (OC) patients. The purpose of this study was to analyze the scientometric characteristics and research trends of LNM in OC.Materials and methods
All the papers on LNM in OC were comprehensively retrieved from the Scopus database. The years of publication were divided into before 2016 and after 2016 in the analysis of research trends.Results
There were 946 papers on LNM in OC, with total citations of 21,154 and the h index of 70. The trend of clinical aspect including lymph node excision, lymphadenectomy, and sentinel lymph node biopsy has changed to early cancer, extranodal extension, chemoradiotherapy, and distant metastasis after 2016. The trend of diagnostic aspect has highlighted depth of invasion, perineural invasion, deep learning, machine learning, nomogram, and diagnostic imaging by PET-CT, contrast enhancement, and radiomics. Moreover, the trend of laboratory investigation including immunoenzyme techniques, neoplasm proteins, and VEGF-C has changed to tumor microenvironment, tumor differentiation, and signal transduction after 2016. There have always been common keywords such as neck dissection, tongue tumor, metabolism, genetics, risk factor, tumor marker, cancer surgery, cisplatin, and cancer radiotherapy.Conclusion
This scientometric study for the first time elucidated the current scenario and research trends of LNM in OC, particularly the comprehensive identification and recognition of the important research topics concerned.
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BibTeX
@article{huang2026scientometric,
title = {{A scientometric study on research trends and characteristics of lymph node metastasis in oral cancer.}},
author = {Linjian Huang and Xiaocui Tong and Wei Liu and Xinyu Zhang},
journal = {Journal of dental sciences},
year = {2026},
month = oct,
doi = {10.1016/j.jds.2025.07.3516},
url = {https://europepmc.org/article/MED/42924131},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - A scientometric study on research trends and characteristics of lymph node metastasis in oral cancer.
AU - Linjian Huang
AU - Xiaocui Tong
AU - Wei Liu
AU - Xinyu Zhang
PY - 2026
DA - 2026/10/01
JO - Journal of dental sciences
DO - 10.1016/j.jds.2025.07.3516
UR - https://europepmc.org/article/MED/42924131
AB - Background/purpose Cervical lymph node metastasis (LNM) is the most critical prognostic factor in oral cancer (OC) patients. The purpose of this study was to analyze the scientometric characteristics and research trends of LNM in OC.Materials and methods All the papers on LNM in OC were comprehensively retrieved from the Scopus database. The years of publication were divided into before 2016 and after 2016 in the analysis of research trends.Results There were 946 papers on LNM in OC, with total citations of 21,154 and the h index of 70. The trend of clinical aspect including lymph node excision, lymphadenectomy, and sentinel lymph node biopsy has changed to early cancer, extranodal extension, chemoradiotherapy, and distant metastasis after 2016. The trend of diagnostic aspect has highlighted depth of invasion, perineural invasion, deep learning, machine learning, nomogram, and diagnostic imaging by PET-CT, contrast enhancement, and radiomics. Moreover, the trend of laboratory investigation including immunoenzyme techniques, neoplasm proteins, and VEGF-C has changed to tumor microenvironment, tumor differentiation, and signal transduction after 2016. There have always been common keywords such as neck dissection, tongue tumor, metabolism, genetics, risk factor, tumor marker, cancer surgery, cisplatin, and cancer radiotherapy.Conclusion This scientometric study for the first time elucidated the current scenario and research trends of LNM in OC, particularly the comprehensive identification and recognition of the important research topics concerned.
SN - 1991-7902
SN - 2213-8862
ER -