Successful Treatment with Surgical Resection for Nocardia cyriacigeorgica Infection in Pulmonary Sequestration
Abstract
Pulmonary sequestration is a congenital lung malformation involving the systemic arterial blood. Infection is a common complication; however, Nocardia infection is rare. We report the case of a 55-year-old immunocompetent male with recurrent infection of a pulmonary cyst in the left lower lobe. Despite the use of empirical antibiotics, the inflammation recurred. Contrast-enhanced computed tomography confirmed pulmonary sequestration, and bronchoscopy revealed Nocardia cyriacigeorgica. Although trimethoprim-sulfamethoxazole was effective, it was discontinued because of severe drug-induced rash. Surgical resection resolved the infection without the use of long-term antibiotics. Timely consideration of surgical intervention may be important for infection control in pulmonary sequestration complicated by Nocardia, especially when antibiotic management is difficult.
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BibTeX
@article{tsukaguchi2026successful,
title = {{Successful Treatment with Surgical Resection for Nocardia cyriacigeorgica Infection in Pulmonary Sequestration}},
author = {Akihiro Tsukaguchi and Takafumi Iguchi and Kosuke Mitsuyuki and Yuki Iwahashi and Yu Kurahara and Takehiko Kobayashi and Takayuki Takimoto and Kazunari Tsuyuguchi},
journal = {Internal Medicine},
year = {2026},
month = aug,
doi = {10.2169/internalmedicine.5945-25},
url = {https://www.jstage.jst.go.jp/article/internalmedicine/65/16/65_5945-25/_article},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Successful Treatment with Surgical Resection for Nocardia cyriacigeorgica Infection in Pulmonary Sequestration
AU - Akihiro Tsukaguchi
AU - Takafumi Iguchi
AU - Kosuke Mitsuyuki
AU - Yuki Iwahashi
AU - Yu Kurahara
AU - Takehiko Kobayashi
AU - Takayuki Takimoto
AU - Kazunari Tsuyuguchi
PY - 2026
DA - 2026/08/15
JO - Internal Medicine
DO - 10.2169/internalmedicine.5945-25
UR - https://www.jstage.jst.go.jp/article/internalmedicine/65/16/65_5945-25/_article
AB - Pulmonary sequestration is a congenital lung malformation involving the systemic arterial blood. Infection is a common complication; however, Nocardia infection is rare. We report the case of a 55-year-old immunocompetent male with recurrent infection of a pulmonary cyst in the left lower lobe. Despite the use of empirical antibiotics, the inflammation recurred. Contrast-enhanced computed tomography confirmed pulmonary sequestration, and bronchoscopy revealed Nocardia cyriacigeorgica. Although trimethoprim-sulfamethoxazole was effective, it was discontinued because of severe drug-induced rash. Surgical resection resolved the infection without the use of long-term antibiotics. Timely consideration of surgical intervention may be important for infection control in pulmonary sequestration complicated by Nocardia, especially when antibiotic management is difficult.
SN - 1349-7235
SN - 0918-2918
ER -