Adrenal Incidentaloma Presenting with Testicular Swelling and Transient Tumor Regression on Computed…

Abstract

Adrenal incidentalomas are typically monitored for tumor growth during follow-up visits. We report the case of a 70-year-old man with a non-functioning left adrenal mass that exhibited transient regression and was ultimately diagnosed as diffuse large B-cell lymphoma. The diagnosis was suspected based on elevated serum lactate dehydrogenase levels and left testicular enlargement, prompting an evaluation using fluorodeoxyglucose positron emission tomography/computed tomography and confirmation by radical orchiectomy. This case highlights the importance of considering malignant lymphoma when adrenal masses regress transiently and underscores the risk of adrenal insufficiency even after the completion of lymphoma treatment.

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BibTeX RIS

BibTeX

@article{sazumi2026adrenal,
  title = {{Adrenal Incidentaloma Presenting with Testicular Swelling and Transient Tumor Regression on Computed Tomography}},
  author = {Yosuke Sazumi and Yasuhiro Nakano and Atsushi Kato and Atsuhito Suyama and Kohei Oguni and Koichiro Yamamoto and Miho Yasuda and Kanako Ochi and Yuya Kawago and Nobuharu Fujii and Fumio Otsuka},
  journal = {Internal Medicine},
  year = {2026},
  month = jul,
  doi = {10.2169/internalmedicine.7332-26},
  url = {https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7332-26/_article},
  note = {CC BY-NC-ND},
}

RIS

TY  - JOUR
TI  - Adrenal Incidentaloma Presenting with Testicular Swelling and Transient Tumor Regression on Computed Tomography
AU  - Yosuke Sazumi
AU  - Yasuhiro Nakano
AU  - Atsushi Kato
AU  - Atsuhito Suyama
AU  - Kohei Oguni
AU  - Koichiro Yamamoto
AU  - Miho Yasuda
AU  - Kanako Ochi
AU  - Yuya Kawago
AU  - Nobuharu Fujii
AU  - Fumio Otsuka
PY  - 2026
DA  - 2026/07/11
JO  - Internal Medicine
DO  - 10.2169/internalmedicine.7332-26
UR  - https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7332-26/_article
AB  - Adrenal incidentalomas are typically monitored for tumor growth during follow-up visits. We report the case of a 70-year-old man with a non-functioning left adrenal mass that exhibited transient regression and was ultimately diagnosed as diffuse large B-cell lymphoma. The diagnosis was suspected based on elevated serum lactate dehydrogenase levels and left testicular enlargement, prompting an evaluation using fluorodeoxyglucose positron emission tomography/computed tomography and confirmation by radical orchiectomy. This case highlights the importance of considering malignant lymphoma when adrenal masses regress transiently and underscores the risk of adrenal insufficiency even after the completion of lymphoma treatment.
SN  - 1349-7235
SN  - 0918-2918
ER  -

Abstract

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