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Peer-reviewedCC BY-NC 4.0Dermatology and Therapy

International Validation of the Short Version of the Quality of Life Relevance-Acne Questionnaire

  • Pavel V. Chernyshov1
  • Nives Pustišek2
  • Dimitra Koumaki3
  • Tetiana Pochynok4
  • Hilayda Karakok Kisla5,6
  • Liana Manolache7
  • Carmen Salavastru8
  • Alina Suru8
  • Adelina Sendrea8
  • Razvigor Darlenski9,10
  • Michael J. Boffa11,12
  • Petra Magri Gatt11
3 more authors
  • Jean-Paul Claudel13
  • Nicole Auffret14
  • Brigitte Dréno15
15 affiliations
  1. 1Department of Dermatology and Venereology, National Medical University, Kiev, Ukraine
  2. 2Children’s Hospital Zagreb, Zagreb, Croatia
  3. 32nd Department of Dermatology and Venereology, National and Kapodistrian University of Athens, Medical School, “Attikon” General University Hospital, Athens, Greece
  4. 4Department of Pediatrics Number 1, National Medical University, Kiev, Ukraine
  5. 5Department of Medical Educational Sciences and Informatics, Hacettepe University Medical School, Ankara, Turkey
  6. 6Private Practice of Dermatology and Venerology of Dr Hilayda Karakök, Ordu, Turkey
  7. 7Dermatology, Dali Medical, Bucharest, Romania
  8. 8Department of Paediatric Dermatology, Colentina Clinical Hospital, ``Carol Davila’’ University of Medicine and Pharmacy, Bucharest, Romania
  9. 9Department of Dermatology and Venereology, Medical Faculty, Trakia University, Stara Zagora, Bulgaria
  10. 10Department of Dermatology and Venereology, Acibadem City Clinic Tokuda Hospital, Sofia, Bulgaria
  11. 11Department of Dermatology, Mater Dei Hospital, Msida, Malta
  12. 12University of South Wales, Wales, UK
  13. 13Private Practice of Dermatology and Venerology, Tours, France
  14. 14Private Practice of Dermatology and Venerology, Paris, France
  15. 15INSERM, Immunology and New Concepts in ImmunoTherapy, INCIT, Nantes Université, Univ Angers, Nantes, France
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Abstract

Introduction: The objective of the present study was to conduct an international validation of the Quality of Life Relevance-Acne Short Version (QOLRELEVANCE-ACNE-SV) and to propose a severity grading system for its scores.

Methods: All patients were asked to fill in the QOLRELEVANCE-ACNE-SV and Dermatology Life Quality Index (DLQI). Global acne severity was assessed separately by dermatologists and patients. Students without acne were asked to fill in the QOLRELEVANCE-ACNE-SV questionnaire on a voluntary basis.

Results: The results of 530 patients with acne across five countries that collected more than 100 results each (Croatia, Greece, Ukraine, Turkey and Romania) were analysed. The results from France, Bulgaria and Malta that collected fewer results were used for assessment of internal consistency. The results from Bulgaria were also used to check test–retest reliability. Cronbach’s alpha was 0.84–0.95 in all countries except Bulgaria and Malta (0.74 and 0.75, respectively). Correlations between QOLRELEVANCE-ACNE-SV scores and DLQI scores were 0.54–0.85 except for Turkey (0.33); mean global acne severity assessed by a dermatologist 0.44–0.90 and self-assessment of the global acne severity 0.45–0.88 except for Romania (0.28 and 0.38, respectively). Among volunteers without acne, all QOLRELEVANCE-ACNE-SV questionnaire scores were 0. Test–retest reliability of the QOLRELEVANCE-ACNE-SV was good (r = 0.90, p < 0.001). The following grading system of the QOLRELEVANCE-ACNE-SV scores was accepted: total scores < 6 correspond to a mild effect, scores from 6 to 8 correspond to moderate effect and scores > 8 correspond to severe effect on a patient’s life.

Conclusions: Our study confirmed high specificity of the QOLRELEVANCE-ACNE-SV questionnaire for patients with acne, good test–retest reliability, good or excellent internal consistency in all countries except Bulgaria and Malta, where it rated as acceptable, good or moderate convergent validity with DLQI (except Turkey) and with global acne severity (except Romania). A grading system of the QOLRELEVANCE-ACNE-SV questionnaire scores was accepted.

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Cite

BibTeXRIS
BibTeX
@article{chernyshov2026international,
  title = {{International Validation of the Short Version of the Quality of Life Relevance-Acne Questionnaire}},
  author = {Pavel V. Chernyshov and Nives Pustišek and Dimitra Koumaki and Tetiana Pochynok and Hilayda Karakok Kisla and Liana Manolache and Carmen Salavastru and Alina Suru and Adelina Sendrea and Razvigor Darlenski and Michael J. Boffa and Petra Magri Gatt and Jean-Paul Claudel and Nicole Auffret and Brigitte Dréno},
  journal = {Dermatology and Therapy},
  year = {2026},
  month = oct,
  doi = {10.1007/s13555-026-01941-5},
  url = {https://doi.org/10.1007/s13555-026-01941-5},
  note = {CC BY-NC 4.0},
}
RIS
TY  - JOUR
TI  - International Validation of the Short Version of the Quality of Life Relevance-Acne Questionnaire
AU  - Pavel V. Chernyshov
AU  - Nives Pustišek
AU  - Dimitra Koumaki
AU  - Tetiana Pochynok
AU  - Hilayda Karakok Kisla
AU  - Liana Manolache
AU  - Carmen Salavastru
AU  - Alina Suru
AU  - Adelina Sendrea
AU  - Razvigor Darlenski
AU  - Michael J. Boffa
AU  - Petra Magri Gatt
AU  - Jean-Paul Claudel
AU  - Nicole Auffret
AU  - Brigitte Dréno
PY  - 2026
DA  - 2026/10/01
JO  - Dermatology and Therapy
DO  - 10.1007/s13555-026-01941-5
UR  - https://doi.org/10.1007/s13555-026-01941-5
AB  - Introduction: The objective of the present study was to conduct an international validation of the Quality of Life Relevance-Acne Short Version (QOLRELEVANCE-ACNE-SV) and to propose a severity grading system for its scores.  Methods: All patients were asked to fill in the QOLRELEVANCE-ACNE-SV and Dermatology Life Quality Index (DLQI). Global acne severity was assessed separately by dermatologists and patients. Students without acne were asked to fill in the QOLRELEVANCE-ACNE-SV questionnaire on a voluntary basis.  Results: The results of 530 patients with acne across five countries that collected more than 100 results each (Croatia, Greece, Ukraine, Turkey and Romania) were analysed. The results from France, Bulgaria and Malta that collected fewer results were used for assessment of internal consistency. The results from Bulgaria were also used to check test–retest reliability. Cronbach’s alpha was 0.84–0.95 in all countries except Bulgaria and Malta (0.74 and 0.75, respectively). Correlations between QOLRELEVANCE-ACNE-SV scores and DLQI scores were 0.54–0.85 except for Turkey (0.33); mean global acne severity assessed by a dermatologist 0.44–0.90 and self-assessment of the global acne severity 0.45–0.88 except for Romania (0.28 and 0.38, respectively). Among volunteers without acne, all QOLRELEVANCE-ACNE-SV questionnaire scores were 0. Test–retest reliability of the QOLRELEVANCE-ACNE-SV was good (r = 0.90, p < 0.001). The following grading system of the QOLRELEVANCE-ACNE-SV scores was accepted: total scores < 6 correspond to a mild effect, scores from 6 to 8 correspond to moderate effect and scores > 8 correspond to severe effect on a patient’s life.  Conclusions: Our study confirmed high specificity of the QOLRELEVANCE-ACNE-SV questionnaire for patients with acne, good test–retest reliability, good or excellent internal consistency in all countries except Bulgaria and Malta, where it rated as acceptable, good or moderate convergent validity with DLQI (except Turkey) and with global acne severity (except Romania). A grading system of the QOLRELEVANCE-ACNE-SV questionnaire scores was accepted.
SN  - 2193-8210
SN  - 2190-9172
ER  -