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Peer-reviewedLicence not statedCancer Discovery

First-in-Human Testing of a Mutant KRAS Vaccine for Pancreatic Cancer Interception in High-risk Cohorts

  • Saurav Daniel Haldar1,2,3,4
  • Amanda L. Huff1,2,3
  • Hejia Henry Wang1,2,5,3,6
  • Zirui Zhu1,2,3
  • Maureen Berg2,3
  • Jiayun Lu2,3
  • Nancy Sun2,3
  • Elizabeth Abou Diwan1,7
  • Hassan Sinan1,8
  • Christopher J. Thoburn1,2,3
  • Matthew Z. Guo2,3
  • Takeichi Yoshida9
16 more authors
  • Linda Chi Hang Chu10
  • Anna K. Ferguson2,3
  • Dimitrios N. Sidiropoulos1,2,3
  • Luciane Tsukamoto Kagohara1,2,3
  • Won Jin Ho1,2,3
  • Katherine M. Bever1,2,3
  • Marina Baretti1,2,3
  • Mark M. Yarchoan1,2,3
  • Daniel A. Laheru1,2,3
  • Julie M. Nauroth1,2,3
  • Amy M. Thomas1,2,3
  • Hao Wang1,2,5,3,6
  • Nilofer Saba Azad1,2,3
  • Michael Goggins7,9,2,3
  • Elizabeth M. Jaffee1,2,3
  • Neeha Zaidi1,2,3
10 affiliations
  1. 12Johns Hopkins Convergence Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland
  2. 2Johns Hopkins University 3 Department of Oncology, , , Baltimore, Maryland
  3. 3Sidney Kimmel Comprehensive Cancer Center 3 Department of Oncology, , , Baltimore, Maryland
  4. 4The University of Texas MD Anderson Cancer Center 1 Department of Gastrointestinal Medical Oncology, , Houston, Texas
  5. 5Johns Hopkins University 8 Division of Quantitative Sciences, Department of Oncology, , , Baltimore, Maryland
  6. 6Sidney Kimmel Comprehensive Cancer Center 8 Division of Quantitative Sciences, Department of Oncology, , , Baltimore, Maryland
  7. 74Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland
  8. 8Icahn School of Medicine at Mount Sinai 5 Elmhurst Hospital Center, , New York, New York
  9. 96Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland
  10. 107Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland
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Cite

BibTeXRIS
BibTeX
@article{haldar2026firstinhuman,
  title = {{First-in-Human Testing of a Mutant KRAS Vaccine for Pancreatic Cancer Interception in High-risk Cohorts}},
  author = {Saurav Daniel Haldar and Amanda L. Huff and Hejia Henry Wang and Zirui Zhu and Maureen Berg and Jiayun Lu and Nancy Sun and Elizabeth Abou Diwan and Hassan Sinan and Christopher J. Thoburn and Matthew Z. Guo and Takeichi Yoshida and Linda Chi Hang Chu and Anna K. Ferguson and Dimitrios N. Sidiropoulos and Luciane Tsukamoto Kagohara and Won Jin Ho and Katherine M. Bever and Marina Baretti and Mark M. Yarchoan and Daniel A. Laheru and Julie M. Nauroth and Amy M. Thomas and Hao Wang and Nilofer Saba Azad and Michael Goggins and Elizabeth M. Jaffee and Neeha Zaidi},
  journal = {Cancer Discovery},
  year = {2026},
  month = jul,
  doi = {10.1158/2159-8290.cd-25-2245},
  url = {https://pmc.ncbi.nlm.nih.gov/articles/PMC13450700/},
}
RIS
TY  - JOUR
TI  - First-in-Human Testing of a Mutant KRAS Vaccine for Pancreatic Cancer Interception in High-risk Cohorts
AU  - Saurav Daniel Haldar
AU  - Amanda L. Huff
AU  - Hejia Henry Wang
AU  - Zirui Zhu
AU  - Maureen Berg
AU  - Jiayun Lu
AU  - Nancy Sun
AU  - Elizabeth Abou Diwan
AU  - Hassan Sinan
AU  - Christopher J. Thoburn
AU  - Matthew Z. Guo
AU  - Takeichi Yoshida
AU  - Linda Chi Hang Chu
AU  - Anna K. Ferguson
AU  - Dimitrios N. Sidiropoulos
AU  - Luciane Tsukamoto Kagohara
AU  - Won Jin Ho
AU  - Katherine M. Bever
AU  - Marina Baretti
AU  - Mark M. Yarchoan
AU  - Daniel A. Laheru
AU  - Julie M. Nauroth
AU  - Amy M. Thomas
AU  - Hao Wang
AU  - Nilofer Saba Azad
AU  - Michael Goggins
AU  - Elizabeth M. Jaffee
AU  - Neeha Zaidi
PY  - 2026
DA  - 2026/07/16
JO  - Cancer Discovery
DO  - 10.1158/2159-8290.cd-25-2245
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC13450700/
SN  - 2159-8274
SN  - 2159-8290
ER  -