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Peer-reviewedCC BY-NCRSC Advances

Isatin derivatives as potent cholinesterase inhibitors: recent developments and future challenges

Abstract

-substitution, and molecular hybridization on inhibitory potency and selectivity. This review summarizes the most promising isatin-based cholinesterase inhibitors reported from 2020 to the present, highlighting their biological activities, structure-activity relationships, and potential for the development of next-generation anti-Alzheimer therapeutics.

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BibTeX
@article{shahzad2026isatin,
  title = {{Isatin derivatives as potent cholinesterase inhibitors: recent developments and future challenges}},
  author = {Muhammad Shahzad and Alia Mushtaq and Christophe Rochais and Muhammad Moazzam Naseer},
  journal = {RSC Advances},
  year = {2026},
  month = sep,
  doi = {10.1039/d6ra06493k},
  url = {https://normandie-univ.hal.science/hal-05767891v1},
  note = {CC BY-NC},
}
RIS
TY  - JOUR
TI  - Isatin derivatives as potent cholinesterase inhibitors: recent developments and future challenges
AU  - Muhammad Shahzad
AU  - Alia Mushtaq
AU  - Christophe Rochais
AU  - Muhammad Moazzam Naseer
PY  - 2026
DA  - 2026/09/28
JO  - RSC Advances
DO  - 10.1039/d6ra06493k
UR  - https://normandie-univ.hal.science/hal-05767891v1
AB  - -substitution, and molecular hybridization on inhibitory potency and selectivity. This review summarizes the most promising isatin-based cholinesterase inhibitors reported from 2020 to the present, highlighting their biological activities, structure-activity relationships, and potential for the development of next-generation anti-Alzheimer therapeutics.
SN  - 2046-2069
ER  -