Skip to content
DraconiticResearch
Search Sources API
203,234 studies31 sourcesUpdated 51 min ago
Peer-reviewedLicence not statedNature Immunology

Functional and dysfunctional T regulatory cell states in human tissues in RA and other autoimmune arthritic diseases

  • Byunghee Koh1,2
  • Shani Talia Gal-Oz3,4,5,6
  • Ryota Sato5,7,6
  • Hung Nguyen8,6
  • Garrett S. Dunlap5,6
  • Christopher B. Mahony9,10
  • Chrissy Bolton11,12,9,10
  • Accelerating Medicines Partnership (AMP) RA/SLE Network13
  • Lucy R. Wedderburn11,14,10
  • Adam P. Croft15,9,16
  • Laura T. Donlin17,18,19
  • Melanie H. Smith17,18,6
4 more authors
  • Soumya Raychaudhuri20,21,4,5,22,6
  • Ilya Korsunsky3,4,5,6
  • Deepak A. Rao5
  • Michael B. Brenner23
23 affiliations
  1. 1Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. [email protected]
  2. 2Brigham and Women's hospital
  3. 3Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA
  4. 4Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA
  5. 5Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA
  6. 6Brigham and Women's Hospital
  7. 7Oncology & Immunology Unit, Research Division, Mitsubishi Tanabe Pharma Corporation, Kanagawa, Japan
  8. 8Department of Medicine, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA
  9. 9Rheumatology Research Group, Department of Inflammation and Ageing, College of Medicine & Health, University of Birmingham, Birmingham, UK
  10. 10University of Birmingham
  11. 11Infection, Immunity and Inflammation Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK
  12. 12Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK
  13. 13University College London
  14. 14NIHR-Biomedical Research Centre at Great Ormond Street Hospital, London, UK
  15. 15National Institute for Health and Care Research (NIHR) Birmingham Biomedical Research Centre, Birmingham, UK
  16. 16Hospital for Special Surgery
  17. 17Hospital for Special Surgery, New York, NY, USA
  18. 18Weill Cornell Medicine, New York, NY, USA
  19. 19Broad Institute
  20. 20Center for Data Sciences, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA
  21. 21Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA
  22. 22Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA
  23. 23Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. [email protected]
Open at sourcePDFDOICite

Related

  1. Regulatory T Cells Across Oral Diseases: A Narrative Review on a Functional Perspective.
    Yu Katsuma, Eiko Sakai, Yoshinori Sumita
    International journal of molecular sciencesPeer-reviewedCC BYFull textImmunologyEurope PMC
  2. Notch3 destabilizes regulatory T cells to drive autoimmune neuroinflammation in multiple sclerosis
    Mehdi Benamar, Paola Contini, Klaus Schmitz-Abe +20
    ImmunityPeer-reviewedLicence not statedFull text17 citedImmunologyHAL
  3. MAKAAO, an open access resource linking human autoantibodies and autoimmune diseases
    Fabien Maury, Solène Grosdidier, Killian Halberda +10
    Communications MedicinePeer-reviewedCC BY 4.0Full textImmunologyHAL
  4. Epigenomic insights into CD4+ T-cell–mediated pathogenesis in autoimmune diseases
    Manaka Goto, Hiroyuki Teruya, Tomohisa Okamura +1
    Frontiers in ImmunologyPeer-reviewedCC BY 4.0Full textImmunologyCrossref
  5. Rituximab-induced hypogammaglobulinemia in autoimmune cytopenia and associated diseases.
    Jonathan Sormani, Alexandre Belot, David Goncalves +10
    La Revue de Médecine InternePeer-reviewedCC BYGeneral biologyEpidemiology & public healthHAL

Cite

BibTeXRIS
BibTeX
@article{koh2026functional,
  title = {{Functional and dysfunctional T regulatory cell states in human tissues in RA and other autoimmune arthritic diseases}},
  author = {Byunghee Koh and Shani Talia Gal-Oz and Ryota Sato and Hung Nguyen and Garrett S. Dunlap and Christopher B. Mahony and Chrissy Bolton and Accelerating Medicines Partnership (AMP) RA/SLE Network and Lucy R. Wedderburn and Adam P. Croft and Laura T. Donlin and Melanie H. Smith and Soumya Raychaudhuri and Ilya Korsunsky and Deepak A. Rao and Michael B. Brenner},
  journal = {Nature Immunology},
  year = {2026},
  month = jun,
  doi = {10.1038/s41590-026-02540-4},
  url = {https://doi.org/10.1101/2025.09.23.677874},
}
RIS
TY  - JOUR
TI  - Functional and dysfunctional T regulatory cell states in human tissues in RA and other autoimmune arthritic diseases
AU  - Byunghee Koh
AU  - Shani Talia Gal-Oz
AU  - Ryota Sato
AU  - Hung Nguyen
AU  - Garrett S. Dunlap
AU  - Christopher B. Mahony
AU  - Chrissy Bolton
AU  - Accelerating Medicines Partnership (AMP) RA/SLE Network
AU  - Lucy R. Wedderburn
AU  - Adam P. Croft
AU  - Laura T. Donlin
AU  - Melanie H. Smith
AU  - Soumya Raychaudhuri
AU  - Ilya Korsunsky
AU  - Deepak A. Rao
AU  - Michael B. Brenner
PY  - 2026
DA  - 2026/06/16
JO  - Nature Immunology
DO  - 10.1038/s41590-026-02540-4
UR  - https://doi.org/10.1101/2025.09.23.677874
SN  - 1529-2908
SN  - 1529-2916
ER  -