A Comprehensive Assessment of Replacing Soybean Meal with Candida Utilis-Fermented Corn Steep Liquor in Broiler Diets: Nutritional Evaluation, Growth Performance, Nutrient Digestibility, Intestinal Health and Serum Biochemical.
- 1State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, No. 2, Yuanmingyuan West Road, Haidian District, Beijing 100193, China.
- 2Ningxia Eppen Biotech Co., Ltd., Yinchuan 750100, China.
Abstract
This study aimed to systematically evaluate the potential of Candida utilis-fermented corn steep liquor (CU-FCSL) to replace soybean meal (SBM) in broiler diets. A total of 72 twenty-one-day-old Arbor Acres Plus broilers (six replicates of six birds) were fed basal or test diets (20% substitution) to determine metabolizable energy. The same design was used to determine standardized ileal amino acid digestibility (SID), with an additional nitrogen-free diet group. In a 42-day growth trial, 288 one-day-old broilers were assigned to control, 2%, 4%, or 6% CU-FCSL diets (six replicates of 12 birds). The results showed that CU-FCSL contained AME 11.36 MJ/kg DM and AMEn 11.31 MJ/kg DM, including SID values of Lys (90.00%), Met (94.01%), Thr (84.63%), and Val (88.86%). Compared with the control, broilers fed 2% or 4% CU-FCSL consistently exhibited greater body weight and weight gain across all phases, whereas 6% inclusion impaired growth performance (p < 0.05). The 4% level improved ether extract digestibility, immune parameters, and intestinal villus height-to-crypt depth ratio, whereas 6% inclusion increased abdominal fat, elevated serum uric acid and ALT, decreased serum IgG, IgM, and IL-10, and inhibited intestinal development and health. In conclusion, 2% and 4% CU-FCSL could be added to replace SBM without adverse effects on broiler health.
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BibTeX
@article{chen2026comprehensive,
title = {{A Comprehensive Assessment of Replacing Soybean Meal with Candida Utilis-Fermented Corn Steep Liquor in Broiler Diets: Nutritional Evaluation, Growth Performance, Nutrient Digestibility, Intestinal Health and Serum Biochemical.}},
author = {Li Chen and Jiankun Feng and Jiamin He and Fang Zhao and Jianmin Yuan},
journal = {Animals : an open access journal from MDPI},
year = {2026},
month = oct,
doi = {10.3390/ani16193117},
url = {https://europepmc.org/article/MED/42883086},
note = {CC BY},
}
RIS
TY - JOUR
TI - A Comprehensive Assessment of Replacing Soybean Meal with Candida Utilis-Fermented Corn Steep Liquor in Broiler Diets: Nutritional Evaluation, Growth Performance, Nutrient Digestibility, Intestinal Health and Serum Biochemical.
AU - Li Chen
AU - Jiankun Feng
AU - Jiamin He
AU - Fang Zhao
AU - Jianmin Yuan
PY - 2026
DA - 2026/10/04
JO - Animals : an open access journal from MDPI
DO - 10.3390/ani16193117
UR - https://europepmc.org/article/MED/42883086
AB - This study aimed to systematically evaluate the potential of Candida utilis-fermented corn steep liquor (CU-FCSL) to replace soybean meal (SBM) in broiler diets. A total of 72 twenty-one-day-old Arbor Acres Plus broilers (six replicates of six birds) were fed basal or test diets (20% substitution) to determine metabolizable energy. The same design was used to determine standardized ileal amino acid digestibility (SID), with an additional nitrogen-free diet group. In a 42-day growth trial, 288 one-day-old broilers were assigned to control, 2%, 4%, or 6% CU-FCSL diets (six replicates of 12 birds). The results showed that CU-FCSL contained AME 11.36 MJ/kg DM and AMEn 11.31 MJ/kg DM, including SID values of Lys (90.00%), Met (94.01%), Thr (84.63%), and Val (88.86%). Compared with the control, broilers fed 2% or 4% CU-FCSL consistently exhibited greater body weight and weight gain across all phases, whereas 6% inclusion impaired growth performance (p < 0.05). The 4% level improved ether extract digestibility, immune parameters, and intestinal villus height-to-crypt depth ratio, whereas 6% inclusion increased abdominal fat, elevated serum uric acid and ALT, decreased serum IgG, IgM, and IL-10, and inhibited intestinal development and health. In conclusion, 2% and 4% CU-FCSL could be added to replace SBM without adverse effects on broiler health.
SN - 2076-2615
ER -