Impact of the Family‐Centered Empowerment Model on Health‐Promoting Lifestyle and Psychological Well‐Being in Patients With Multiple Sclerosis: A Randomized Controlled Clinical Trial
4 affiliations
- 1Student Research Committee, Fasa University of Medical Sciences Fasa Iran
- 2Department of Medical Surgical Nursing School of Nursing, Fasa University of Medical Sciences Fasa Iran
- 3NonCommunicable Diseases Research Center (NCDRC), Fasa University of Medical Sciences Fasa Iran
- 4Community Based Psychiatric Care Research Center Nursing and Midwifery School of Nursing, Shiraz University of Medical Sciences Shiraz Iran
Abstract
Background and Aim: Multiple sclerosis (MS) is a chronic neurological disease that can affect patients’ health‐promoting lifestyle and psychological well‐being and may also place substantial demands on family caregivers. This study aimed to evaluate the effect of a family‐centered empowerment intervention based on the Family‐Centered Empowerment Model (FCEM) on health‐promoting lifestyle and psychological well‐being among patients with MS, with the active involvement of their primary family caregivers.
Methods: This randomized controlled clinical trial was conducted from February to April 2025 at an MS clinic in Fars Province, southern Iran. It included 70 patient‐caregiver dyads, comprising 70 patients with MS and their primary family caregivers. The dyads were randomly assigned to the intervention or control group, with 35 dyads in each group. Patients and caregivers in the intervention group took part in a structured family‐centered empowerment program based on the four‐stage FCEM. The program consisted of five to seven face‐to‐face educational sessions attended jointly by the patients and their primary family caregivers. The control group continued to receive routine care. Health‐promoting lifestyle and psychological well‐being were assessed at baseline, immediately after the intervention, and at the 2‐month follow‐up.
Results: At baseline, the two groups did not differ significantly in health‐promoting lifestyle or psychological well‐being (p > 0.05). Following the intervention, the mean health‐promoting lifestyle score was 126.40 ± 25.18 in the intervention group and 102.62 ± 25.18 in the control group (p < 0.001). At the 2‐month follow‐up, the corresponding scores were 124.34 ± 22.39 and 104.22 ± 20.23, respectively (p < 0.001). A similar pattern was observed for psychological well‐being. Immediately after the intervention, the mean score was 73.68 ± 13.83 in the intervention group, compared with 59.62 ± 10.24 in the control group (p < 0.001). At 2 months, the scores were 71.51 ± 12.82 and 61.34 ± 11.55, respectively (p < 0.001). Within the intervention group, scores increased significantly from baseline to both the post‐intervention assessment and the 2‐month follow‐up (p < 0.001). Changes in the control group were comparatively small.
Conclusion: A family‐centered empowerment intervention based on the FCEM was associated with greater improvements in health‐promoting lifestyle and psychological well‐being among patients with MS compared with routine care. Involving primary family caregivers in MS education and self‐management support may be a useful component of family‐centered care.
Iranian Registry of Clinical Trials: IRCT registration number: IRCT20190917044802N12. Registration date: 10/01/2025.
Related
- mHealth-based lifestyle intervention for hypertension in community-dwelling adults: a cluster-randomized controlled trial with exploratory multi-omics analyses
- Blood Biomarkers of Alzheimer's Disease Neuropathology, Cognition, and Response to a Multidomain Lifestyle Intervention: Secondary analysis of the FINGER Randomized Controlled Dementia Risk Reduction Trial
- Effects of mindfulness-based yoga and physical exercise on psychological well-being in individuals with visual impairment: a three-armed randomized controlled trial
- Promoting psychological resilience during the perinatal period with a digital tool (the HealthyMoms4MentalHealth-app): a study protocol for a randomised controlled trial in Sweden
- Reducing sedentary behavior and promoting physical activity in medical students: protocol of the PROMESS-Physical Activity randomized controlled clinical trial
BibTeX
@article{ranjber2026impact,
title = {{Impact of the Family‐Centered Empowerment Model on Health‐Promoting Lifestyle and Psychological Well‐Being in Patients With Multiple Sclerosis: A Randomized Controlled Clinical Trial}},
author = {Leila Ranjber and Mostafa Bijani and Azizallah Dehghan and Roya Dokoohaki and Azam Zare},
journal = {Health Science Reports},
year = {2026},
month = oct,
doi = {10.1002/hsr2.73423},
url = {https://doi.org/10.1002/hsr2.73423},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Impact of the Family‐Centered Empowerment Model on Health‐Promoting Lifestyle and Psychological Well‐Being in Patients With Multiple Sclerosis: A Randomized Controlled Clinical Trial
AU - Leila Ranjber
AU - Mostafa Bijani
AU - Azizallah Dehghan
AU - Roya Dokoohaki
AU - Azam Zare
PY - 2026
DA - 2026/10/26
JO - Health Science Reports
DO - 10.1002/hsr2.73423
UR - https://doi.org/10.1002/hsr2.73423
AB - Background and Aim: Multiple sclerosis (MS) is a chronic neurological disease that can affect patients’ health‐promoting lifestyle and psychological well‐being and may also place substantial demands on family caregivers. This study aimed to evaluate the effect of a family‐centered empowerment intervention based on the Family‐Centered Empowerment Model (FCEM) on health‐promoting lifestyle and psychological well‐being among patients with MS, with the active involvement of their primary family caregivers. Methods: This randomized controlled clinical trial was conducted from February to April 2025 at an MS clinic in Fars Province, southern Iran. It included 70 patient‐caregiver dyads, comprising 70 patients with MS and their primary family caregivers. The dyads were randomly assigned to the intervention or control group, with 35 dyads in each group. Patients and caregivers in the intervention group took part in a structured family‐centered empowerment program based on the four‐stage FCEM. The program consisted of five to seven face‐to‐face educational sessions attended jointly by the patients and their primary family caregivers. The control group continued to receive routine care. Health‐promoting lifestyle and psychological well‐being were assessed at baseline, immediately after the intervention, and at the 2‐month follow‐up. Results: At baseline, the two groups did not differ significantly in health‐promoting lifestyle or psychological well‐being (p > 0.05). Following the intervention, the mean health‐promoting lifestyle score was 126.40 ± 25.18 in the intervention group and 102.62 ± 25.18 in the control group (p < 0.001). At the 2‐month follow‐up, the corresponding scores were 124.34 ± 22.39 and 104.22 ± 20.23, respectively (p < 0.001). A similar pattern was observed for psychological well‐being. Immediately after the intervention, the mean score was 73.68 ± 13.83 in the intervention group, compared with 59.62 ± 10.24 in the control group (p < 0.001). At 2 months, the scores were 71.51 ± 12.82 and 61.34 ± 11.55, respectively (p < 0.001). Within the intervention group, scores increased significantly from baseline to both the post‐intervention assessment and the 2‐month follow‐up (p < 0.001). Changes in the control group were comparatively small. Conclusion: A family‐centered empowerment intervention based on the FCEM was associated with greater improvements in health‐promoting lifestyle and psychological well‐being among patients with MS compared with routine care. Involving primary family caregivers in MS education and self‐management support may be a useful component of family‐centered care. Iranian Registry of Clinical Trials: IRCT registration number: IRCT20190917044802N12. Registration date: 10/01/2025.
SN - 2398-8835
ER -