Visual electrophysiology and neuropsychology in bipolar disorders: A review on current state and perspectives
Abstract
Bipolar disorder is a lifelong condition. Today, there is a urgent need to find indicators of the disease. Specifically, they could be useful to improve the diagnosis and the early detection, the prognosis, to estimate the treatment response and to create homogeneous subgroups of patients based on similar pathophysiological mechanisms. Here, we assume that visual electrophysiology in combination with a neuropsychological assessment can give additional data to routine practice, especially to precise specific damages and pathophysiological characteristics of these patients. Visual electrophysiology is characterized by an electroretinogram and the delivery of visual evoked potentials, which measure retinal and visual cortical neuronal functioning in response to visual stimulations. This review highlights the interest of visual electrophysiology and neuropsychology performed in isolation and to present the benefits of combining these measures. We will review the results based on these measures in patients with bipolar disorders. Finally, we argue for the use of innovative techniques such as signal processing and artificial intelligence techniques for routine care and precision medicine in bipolar disorders.
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BibTeX
@article{tursini2026visual,
title = {{Visual electrophysiology and neuropsychology in bipolar disorders: A review on current state and perspectives}},
author = {Katelyne Tursini and Steven Le Cam and Raymund Schwan and Grégory Gross and Karine Angioi-Duprez and Jean-Baptiste Conart and Irving Remy and Florent Bernardin and Vincent Laprevote and Eléa Knobloch and Tiphaine Ricaud and Aline Rahnema and Valérie Louis Dorr and Thomas Schwitzer},
journal = {Neuroscience and Biobehavioral Reviews},
year = {2026},
month = sep,
doi = {10.1016/j.neubiorev.2022.104764},
url = {https://hal.science/hal-03900049v1},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Visual electrophysiology and neuropsychology in bipolar disorders: A review on current state and perspectives
AU - Katelyne Tursini
AU - Steven Le Cam
AU - Raymund Schwan
AU - Grégory Gross
AU - Karine Angioi-Duprez
AU - Jean-Baptiste Conart
AU - Irving Remy
AU - Florent Bernardin
AU - Vincent Laprevote
AU - Eléa Knobloch
AU - Tiphaine Ricaud
AU - Aline Rahnema
AU - Valérie Louis Dorr
AU - Thomas Schwitzer
PY - 2026
DA - 2026/09/09
JO - Neuroscience and Biobehavioral Reviews
DO - 10.1016/j.neubiorev.2022.104764
UR - https://hal.science/hal-03900049v1
AB - Bipolar disorder is a lifelong condition. Today, there is a urgent need to find indicators of the disease. Specifically, they could be useful to improve the diagnosis and the early detection, the prognosis, to estimate the treatment response and to create homogeneous subgroups of patients based on similar pathophysiological mechanisms. Here, we assume that visual electrophysiology in combination with a neuropsychological assessment can give additional data to routine practice, especially to precise specific damages and pathophysiological characteristics of these patients. Visual electrophysiology is characterized by an electroretinogram and the delivery of visual evoked potentials, which measure retinal and visual cortical neuronal functioning in response to visual stimulations. This review highlights the interest of visual electrophysiology and neuropsychology performed in isolation and to present the benefits of combining these measures. We will review the results based on these measures in patients with bipolar disorders. Finally, we argue for the use of innovative techniques such as signal processing and artificial intelligence techniques for routine care and precision medicine in bipolar disorders.
SN - 0149-7634
SN - 1873-7528
ER -