A case report of sclerosing polycystic adenoma of minor salivary glands.

Abstract

Sclerosing polycystic adenosis (SPA) is a rare tumor of the major or minor salivary glands that is similar to tumors of the breast. SPA has been part of new entries of salivary gland tumor in the World Health Organization Classification since 2022. A 21-years-old female represented in our hospital with a nodule in the upper lip that was present for some months. A conservative surgical excision of the tumor was done and the lesion underwent a histopathologic examination. The immunohistochemical findings (Ki-67 <2%, focal S100, focal p16) supported a benign diagnosis. Histopathological examination describes a biphasic tumor with the presence of multiple cystic dilated ducts in a sclerotic stroma. Less than 100 reported cases have been in the literature.

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BibTeX

@article{mataj2026case,
  title = {{A case report of sclerosing polycystic adenoma of minor salivary glands.}},
  author = {Nela Mataj and Gresa Baboci and Ejona Celiku and Andis Qendro and Dajana Collaku},
  journal = {Journal of surgical case reports},
  year = {2026},
  month = oct,
  doi = {10.1093/jscr/rjag985},
  url = {https://europepmc.org/article/MED/42948485},
  note = {CC BY-NC},
}

RIS

TY  - JOUR
TI  - A case report of sclerosing polycystic adenoma of minor salivary glands.
AU  - Nela Mataj
AU  - Gresa Baboci
AU  - Ejona Celiku
AU  - Andis Qendro
AU  - Dajana Collaku
PY  - 2026
DA  - 2026/10/27
JO  - Journal of surgical case reports
DO  - 10.1093/jscr/rjag985
UR  - https://europepmc.org/article/MED/42948485
AB  - Sclerosing polycystic adenosis (SPA) is a rare tumor of the major or minor salivary glands that is similar to tumors of the breast. SPA has been part of new entries of salivary gland tumor in the World Health Organization Classification since 2022. A 21-years-old female represented in our hospital with a nodule in the upper lip that was present for some months. A conservative surgical excision of the tumor was done and the lesion underwent a histopathologic examination. The immunohistochemical findings (Ki-67 <2%, focal S100, focal p16) supported a benign diagnosis. Histopathological examination describes a biphasic tumor with the presence of multiple cystic dilated ducts in a sclerotic stroma. Less than 100 reported cases have been in the literature.
SN  - 2042-8812
ER  -

Abstract

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