Sleep duration and prostate cancer-specific mortality in the Southern Community Cohort Study.
8 affiliations
- 1Department of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA, USA.
- 2Department of Statistics and Data Science, UCLA College of Letters and Science, Los Angeles, CA, USA.
- 3Department of Public Health, Aarhus University, Aarhus, Denmark.
- 4Department of Pathology and Laboratory Medicine, UCLA David Geffen School of Medicine, Los Angeles, CA, USA.
- 5Department of Preventive Medicine, The University of Tennessee Health Science Center, College of Medicine, Memphis, TN, USA.
- 6Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, CA, USA.
- 7Department of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA, USA. [email protected].
- 8Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, CA, USA. [email protected].
Abstract
Purpose
Sleep patterns may affect metabolic and behavioral processes, which subsequently could be linked to cancer mortality. However, the relationship between sleep patterns and prostate cancer-specific mortality remains unclear. We evaluated the association of sleep and prostate cancer-specific mortality and investigated whether race/ethnicity influences the association.Methods
The Southern Community Cohort Study (SCCS), a prospective cohort study, recruited participants from 12 Southeastern states between March 2002 and September 2009. The cohort included 34,166 males, predominantly Black/African American. Sleep exposures were measured via a baseline questionnaire. Cox Proportional hazards models were used to estimate associations between sleep and prostate cancer-specific mortality and were adjusted for important potential confounders.Results
During follow-up (median 15.9 years), 225 men died from prostate cancer. Longer sleep duration (≥ 9 hours) on weekends versus 7-8 hours was suggestively associated with an increased risk of prostate cancer-specific mortality (hazard ratio (HR)= 1.44, 95% confidence interval (CI): 1.02-2.03). When stratified by race, longer sleep duration was suggestively associated with an increased risk of prostate cancer mortality for both Black and White men, although the associations were insignificant. Overall sleep duration and restless sleep were not associated with prostate cancer-specific mortality.Conclusion
Men reporting ≥ 9 hours of weekend sleep had an elevated risk of prostate cancer-specific mortality compared with those sleeping 7-8 hours. Stratified analysis suggests an increased risk of prostate cancer-specific mortality among both Black men and White men with ≥ 9 hours of sleep versus 7-8 hours, though estimates were imprecise due to small event numbers.
Related
- Associations of Outdoor Air Pollution With Cause-specific Mortality in Metastatic Prostate Cancer: A cohort study
- Development and validation of a competing-risk nomogram for predicting cancer-specific mortality in prostate cancer: a SEER population-based study
- Standardised procalcitonin monitoring and antibiotic duration in community-acquired sepsis: a pragmatic randomised controlled trial
- Progress but not on track: forecasting under-five mortality and the likelihood of achieving SDG target 3.2 in Southern Africa
- Survival Status and Predictors of Mortality Among Women With Breast Cancer in Southern Ethiopia: A Retrospective Cohort Study
BibTeX
@article{anukam2026sleep,
title = {{Sleep duration and prostate cancer-specific mortality in the Southern Community Cohort Study.}},
author = {Danica C Anukam and Roch A Nianogo and Onyebuchi A Arah and Jianyu Rao and Jay H Fowke and Mia Hashibe and Zuo-Feng Zhang},
journal = {Cancer causes \& control : CCC},
year = {2026},
month = oct,
doi = {10.1007/s10552-026-02256-8},
url = {https://europepmc.org/article/MED/42905154},
note = {CC BY},
}
RIS
TY - JOUR
TI - Sleep duration and prostate cancer-specific mortality in the Southern Community Cohort Study.
AU - Danica C Anukam
AU - Roch A Nianogo
AU - Onyebuchi A Arah
AU - Jianyu Rao
AU - Jay H Fowke
AU - Mia Hashibe
AU - Zuo-Feng Zhang
PY - 2026
DA - 2026/10/21
JO - Cancer causes & control : CCC
DO - 10.1007/s10552-026-02256-8
UR - https://europepmc.org/article/MED/42905154
AB - Purpose Sleep patterns may affect metabolic and behavioral processes, which subsequently could be linked to cancer mortality. However, the relationship between sleep patterns and prostate cancer-specific mortality remains unclear. We evaluated the association of sleep and prostate cancer-specific mortality and investigated whether race/ethnicity influences the association.Methods The Southern Community Cohort Study (SCCS), a prospective cohort study, recruited participants from 12 Southeastern states between March 2002 and September 2009. The cohort included 34,166 males, predominantly Black/African American. Sleep exposures were measured via a baseline questionnaire. Cox Proportional hazards models were used to estimate associations between sleep and prostate cancer-specific mortality and were adjusted for important potential confounders.Results During follow-up (median 15.9 years), 225 men died from prostate cancer. Longer sleep duration (≥ 9 hours) on weekends versus 7-8 hours was suggestively associated with an increased risk of prostate cancer-specific mortality (hazard ratio (HR)= 1.44, 95% confidence interval (CI): 1.02-2.03). When stratified by race, longer sleep duration was suggestively associated with an increased risk of prostate cancer mortality for both Black and White men, although the associations were insignificant. Overall sleep duration and restless sleep were not associated with prostate cancer-specific mortality.Conclusion Men reporting ≥ 9 hours of weekend sleep had an elevated risk of prostate cancer-specific mortality compared with those sleeping 7-8 hours. Stratified analysis suggests an increased risk of prostate cancer-specific mortality among both Black men and White men with ≥ 9 hours of sleep versus 7-8 hours, though estimates were imprecise due to small event numbers.
SN - 0957-5243
SN - 1573-7225
ER -