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Peer-reviewedCC BY 4.0OncoImmunology

STAT3 inhibition for the induction of immunogenic cell death in multiple myeloma

  • Oliver Kepp
  • Guido Kroemer
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Abstract

In a recent paper published in Blood Science, Sha et al. report that STAT3 inhibition eliminates multiple myeloma stem-like cells while eliciting hallmarks of immunogenic cell death. These highly intriguing findings connect stemness, integrated stress response, and antitumor immunity, yet in vivo validation remains necessary before this strategy can be considered immunogenic.

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Cite

BibTeXRIS
BibTeX
@article{kepp2026stat3,
  title = {{STAT3 inhibition for the induction of immunogenic cell death in multiple myeloma}},
  author = {Oliver Kepp and Guido Kroemer},
  journal = {OncoImmunology},
  year = {2026},
  month = sep,
  doi = {10.1080/2162402x.2026.2732727},
  url = {https://hal.science/hal-05801062v1},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - STAT3 inhibition for the induction of immunogenic cell death in multiple myeloma
AU  - Oliver Kepp
AU  - Guido Kroemer
PY  - 2026
DA  - 2026/09/15
JO  - OncoImmunology
DO  - 10.1080/2162402x.2026.2732727
UR  - https://hal.science/hal-05801062v1
AB  - In a recent paper published in Blood Science, Sha et al. report that STAT3 inhibition eliminates multiple myeloma stem-like cells while eliciting hallmarks of immunogenic cell death. These highly intriguing findings connect stemness, integrated stress response, and antitumor immunity, yet in vivo validation remains necessary before this strategy can be considered immunogenic.
SN  - 2162-4011
SN  - 2162-402X
ER  -