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Peer-reviewedCC BY-NCMedical principles and practice : international journal of the Kuwait University, Health Science Centre

Perceived Stress, Sleep Quality, and Their Impact on Glycemic Control among Type 2 Diabetes Patients in Riyadh: Cross-Sectional Evidence.

  1. 1Endocrine clinic Al-diriyah hospital (Riyadh third cluster), Riyadh, Saudi Arabia, [email protected].
  2. 2College of Medicine, Almaarefa University, Riyadh, Saudi Arabia.
  3. 3College of Medicine, Shaqraa University, Riyadh, Saudi Arabia.

Abstract

Objective

The aim of this study was to investigate the relationship between perceived stress and sleep quality with glycemic blood levels in T2DM patients in Riyadh.Subject and methods

This cross-sectional study evaluated a total of 309 patients diagnosed with type 2 diabetes mellitus in Riyadh, Saudi Arabia. The study comprised an initial validation and Arabic translation phase involving 160 participants, followed by an analytical phase focusing on 149 adult patients. To investigate the impact of psychosocial and metabolic factors on glycemic control (hemoglobin A1c [HbA1c]), data were collected using the Pittsburgh Sleep Quality Index (PSQI) and the Perceived Stress Scale (PSS-10), alongside clinical metrics such as body mass index (BMI) and dyslipidemia extracted from medical records. A multivariable linear regression model was utilized to identify independent factors associated with glycemic regulation within the local population.Results

The multivariable regression model demonstrated robust explanatory power (adjusted R2 = 0.726, p < 0.001). Traditional risk factors, specifically elevated BMI (β = 0.448, p < 0.001) and dyslipidemia (β = 0.304, p < 0.001), were significantly associated with higher HbA1c levels. Notably, poor sleep quality emerged as a significant independent factor associated with elevated HbA1c (β = 0.261, p < 0.001), whereas perceived stress did not exhibit a significant correlation. Conversely, physical activity demonstrated a significant protective effect, correlating with lower HbA1c (β = -0.271, p < 0.001).Conclusion

Poor sleep quality, rather than perceived psychological stress, is a primary factor independently associated with hyperglycemia in this patient cohort. These findings suggest that standard diabetes care should integrate formal sleep assessments alongside patient care management.

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BibTeX
@article{almutairi2026perceived,
  title = {{Perceived Stress, Sleep Quality, and Their Impact on Glycemic Control among Type 2 Diabetes Patients in Riyadh: Cross-Sectional Evidence.}},
  author = {Reem Almutairi and Abdullah Khattab and Amen Bawazir and Meshal Aljarboua and Abdullah Aljarboua and Dhafer Alshabawi},
  journal = {Medical principles and practice : international journal of the Kuwait University, Health Science Centre},
  year = {2026},
  month = oct,
  doi = {10.1159/mpp/adpag019},
  url = {https://europepmc.org/article/MED/42862788},
  note = {CC BY-NC},
}
RIS
TY  - JOUR
TI  - Perceived Stress, Sleep Quality, and Their Impact on Glycemic Control among Type 2 Diabetes Patients in Riyadh: Cross-Sectional Evidence.
AU  - Reem Almutairi
AU  - Abdullah Khattab
AU  - Amen Bawazir
AU  - Meshal Aljarboua
AU  - Abdullah Aljarboua
AU  - Dhafer Alshabawi
PY  - 2026
DA  - 2026/10/12
JO  - Medical principles and practice : international journal of the Kuwait University, Health Science Centre
DO  - 10.1159/mpp/adpag019
UR  - https://europepmc.org/article/MED/42862788
AB  - Objective  The aim of this study was to investigate the relationship between perceived stress and sleep quality with glycemic blood levels in T2DM patients in Riyadh.Subject and methods  This cross-sectional study evaluated a total of 309 patients diagnosed with type 2 diabetes mellitus in Riyadh, Saudi Arabia. The study comprised an initial validation and Arabic translation phase involving 160 participants, followed by an analytical phase focusing on 149 adult patients. To investigate the impact of psychosocial and metabolic factors on glycemic control (hemoglobin A1c [HbA1c]), data were collected using the Pittsburgh Sleep Quality Index (PSQI) and the Perceived Stress Scale (PSS-10), alongside clinical metrics such as body mass index (BMI) and dyslipidemia extracted from medical records. A multivariable linear regression model was utilized to identify independent factors associated with glycemic regulation within the local population.Results  The multivariable regression model demonstrated robust explanatory power (adjusted R2 = 0.726, p < 0.001). Traditional risk factors, specifically elevated BMI (β = 0.448, p < 0.001) and dyslipidemia (β = 0.304, p < 0.001), were significantly associated with higher HbA1c levels. Notably, poor sleep quality emerged as a significant independent factor associated with elevated HbA1c (β = 0.261, p < 0.001), whereas perceived stress did not exhibit a significant correlation. Conversely, physical activity demonstrated a significant protective effect, correlating with lower HbA1c (β = -0.271, p < 0.001).Conclusion  Poor sleep quality, rather than perceived psychological stress, is a primary factor independently associated with hyperglycemia in this patient cohort. These findings suggest that standard diabetes care should integrate formal sleep assessments alongside patient care management.
SN  - 1011-7571
SN  - 1423-0151
ER  -