Early and Long-Term Results of 101 Consecutive Patients After Transcarotid Transcatheter Aortic Valve Implantation
- 1Department of Cardiac Surgery, Medical University of Silesia, 40-635 Katowice, Poland
- 2Division of Cardiology and Structural Heart Diseases, Medical University of Silesia, 40-635 Katowice, Poland
- 3Department of Electrocardiology and Heart Failure, Medical University of Silesia, 40-635 Katowice, Poland
Abstract
Background/Objectives: Transcatheter aortic valve implantation through the common carotid artery (TC-TAVI) is one of the possible treatment options for patients with ineligible transfemoral approach. The aim of our study was to evaluate the efficacy and safety of patients treated with TC-TAVI in early and long-term follow-up. Methods: The study included patients with severe aortic stenosis treated with TC-TAVI. In-hospital outcomes, early, long-term follow-up were presented in accordance with the VARC-3 recommendations. Results: The analysis presented 101 patients. We observed high procedural success-97% (n = 98). The number of VARC-3 incidents: 3.96% major vascular complications; 0.99% myocardial infarction; 0.99% cardiac tamponade; 0.99% life-threatening bleeding; 3.96% cerebrovascular incidents. The NYHA class decreased significantly compared to the pre-procedure value (2 [1–2] vs. 3 [3–3]; p < 0.001). There was a significant improvement in postprocedural cerebral oximetry values compared to baseline on both the implanted and contralateral sides (67.5 [63–71]% vs. 70 [63.5–75]%; p < 0.05) and (67 [64–71]% vs. 71 [64–76]%; p < 0.05), respectively. The 30-day, 1-year, and 2-year survival rates were 94.1%, 80.2%, and 69.3%, respectively. In the univariate analysis, BAV (HR 4.54; 95% CI: 1.14–17.99; p = 0.03) and LVEF ≤ 35% (HR 7.32; 95% CI: 2.59–20.65; p < 0.001) were significantly associated with two-year mortality. In an exploratory adjusted Cox regression analysis, BAV (HR 2.63; 95% CI: 1.07–6.45; p = 0.03) and LVEF ≤ 35% (HR 3.48; 95% CI: 1.67–7.24; p < 0.001) were associated with higher 2-year mortality. Conclusions: Our single-center, observational report indicated feasibility and good observed outcomes of the TC-TAVI procedure in an experienced clinical team.
Related
- Surgery that looks like transcatheter aortic valve implantation: the transaxillary concept for minimally invasive aortic valve replacement in 1,848 consecutive patients
- Coronary artery disease management in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation: a systematic review and meta-analysis of randomised controlled trials
- Outcomes of Hemodialysis Patients Undergoing Contemporary Transcatheter Aortic Valve Implantation ― Insights From the LAPLACE-TAVI Registry ―
- Prognostic value of preprocedural neutrophil percentage-to-albumin ratio for in-hospital and overall mortality in patients with reduced ejection fraction undergoing transcatheter aortic valve implantation
- Prognostic value of pre- and post-procedural TAPSE/PASP ratio for long-term mortality in patients with left ventricular ejection fraction < 50% undergoing transcatheter aortic valve implantation
BibTeX
@article{hudziak2026early,
title = {{Early and Long-Term Results of 101 Consecutive Patients After Transcarotid Transcatheter Aortic Valve Implantation}},
author = {Damian Hudziak and Monika Gruz-Kwapisz and Radosław Parma and Wojciech Wańha and Sylwia Gładysz-Wańha and Wojciech Wojakowski and Radosław Gocoł},
journal = {Journal of Clinical Medicine},
year = {2026},
month = oct,
doi = {10.3390/jcm15207917},
url = {https://www.mdpi.com/2077-0383/15/20/7917},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Early and Long-Term Results of 101 Consecutive Patients After Transcarotid Transcatheter Aortic Valve Implantation
AU - Damian Hudziak
AU - Monika Gruz-Kwapisz
AU - Radosław Parma
AU - Wojciech Wańha
AU - Sylwia Gładysz-Wańha
AU - Wojciech Wojakowski
AU - Radosław Gocoł
PY - 2026
DA - 2026/10/01
JO - Journal of Clinical Medicine
DO - 10.3390/jcm15207917
UR - https://www.mdpi.com/2077-0383/15/20/7917
AB - Background/Objectives: Transcatheter aortic valve implantation through the common carotid artery (TC-TAVI) is one of the possible treatment options for patients with ineligible transfemoral approach. The aim of our study was to evaluate the efficacy and safety of patients treated with TC-TAVI in early and long-term follow-up. Methods: The study included patients with severe aortic stenosis treated with TC-TAVI. In-hospital outcomes, early, long-term follow-up were presented in accordance with the VARC-3 recommendations. Results: The analysis presented 101 patients. We observed high procedural success-97% (n = 98). The number of VARC-3 incidents: 3.96% major vascular complications; 0.99% myocardial infarction; 0.99% cardiac tamponade; 0.99% life-threatening bleeding; 3.96% cerebrovascular incidents. The NYHA class decreased significantly compared to the pre-procedure value (2 [1–2] vs. 3 [3–3]; p < 0.001). There was a significant improvement in postprocedural cerebral oximetry values compared to baseline on both the implanted and contralateral sides (67.5 [63–71]% vs. 70 [63.5–75]%; p < 0.05) and (67 [64–71]% vs. 71 [64–76]%; p < 0.05), respectively. The 30-day, 1-year, and 2-year survival rates were 94.1%, 80.2%, and 69.3%, respectively. In the univariate analysis, BAV (HR 4.54; 95% CI: 1.14–17.99; p = 0.03) and LVEF ≤ 35% (HR 7.32; 95% CI: 2.59–20.65; p < 0.001) were significantly associated with two-year mortality. In an exploratory adjusted Cox regression analysis, BAV (HR 2.63; 95% CI: 1.07–6.45; p = 0.03) and LVEF ≤ 35% (HR 3.48; 95% CI: 1.67–7.24; p < 0.001) were associated with higher 2-year mortality. Conclusions: Our single-center, observational report indicated feasibility and good observed outcomes of the TC-TAVI procedure in an experienced clinical team.
SN - 2077-0383
ER -