Orthodontic Management in Patients with Amelogenesis Imperfecta: A Narrative Review.
4 affiliations
- 1Department of Dentistry, School of Dentistry, European University Cyprus, Nicosia 2404, Cyprus.
- 2Department of Oral Medicine and Pathology, School of Dentistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
- 3Department of Dentoalveolar Surgery, Surgical Implantology and Radiology, School of Dentistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
- 4Clinic for Operative Dentistry, Periodontology and Preventive Dentistry, University Hospital RWTH Aachen, 52074 Aachen, Germany.
Abstract
Background: Amelogenesis imperfecta affecting enamel formation is frequently associated with a variety of malocclusions and eruption disturbances. Orthodontic treatment is crucial in comprehensive patient management. Previous studies have shown that orthodontic treatment becomes more challenging in patients with AI as the defective enamel affects the bracket bonding, retention of appliances and treatment mechanics and often needs modified bonding protocols, pre-treatment restorative build-ups, skeletal anchorage and general multidisciplinary management. There is no evidence of the ideal orthodontic treatment yet; available evidence only consists of case reports and small observational studies that address specific aspects with no established consensus. Therefore, this narrative review aimed to critically examine the contemporaneous evidence on orthodontic assessment and treatment planning in AI patients, drawing on studies identified through a structured literature search. Materials and Methods: An electronic search of the literature was conducted in the PubMed, Scopus, and ScienceDirect databases. Out of 640 records that were initially identified, 11 studies met the inclusion criteria for qualitative synthesis. Results: Bonding issues resulting from enamel defects tend to be identified as a significant clinical challenge necessitating modified orthodontic techniques. The included studies demonstrated that by using individualized treatment planning, modified bonding procedures, fixed appliances, expansion procedures, skeletal anchorage and combined orthognathic surgery in some cases within the multidisciplinary treatment approach, there can be successful orthodontic management for these patients. Conclusions: Vital steps such as early diagnosis, careful treatment planning, and coordination with restorative and prosthodontic treatment were associated with better functional and esthetic outcomes. Consequently, even though there is limited evidence, the available literature supports a customized interdisciplinary approach as the most predictable and effective strategy for managing orthodontic problems in patients with AI, while emphasizing that case reports and small observational studies are the main sources of current findings.
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BibTeX
@article{syrioti2026orthodontic,
title = {{Orthodontic Management in Patients with Amelogenesis Imperfecta: A Narrative Review.}},
author = {Amalia Syrioti and Faidra Chatzikallinikidou and Christina Charisi and Filippos Fytros and Nikolaos Spantidakis and Panagiota Dimitropoulou and Konstantinos Poulopoulos and Stefanos Zisis and Athanasios Poulopoulos and Vasileios Zisis},
journal = {Reports (MDPI)},
year = {2026},
month = sep,
doi = {10.3390/reports9040321},
url = {https://europepmc.org/article/MED/42924773},
note = {CC BY},
}
RIS
TY - JOUR
TI - Orthodontic Management in Patients with Amelogenesis Imperfecta: A Narrative Review.
AU - Amalia Syrioti
AU - Faidra Chatzikallinikidou
AU - Christina Charisi
AU - Filippos Fytros
AU - Nikolaos Spantidakis
AU - Panagiota Dimitropoulou
AU - Konstantinos Poulopoulos
AU - Stefanos Zisis
AU - Athanasios Poulopoulos
AU - Vasileios Zisis
PY - 2026
DA - 2026/09/23
JO - Reports (MDPI)
DO - 10.3390/reports9040321
UR - https://europepmc.org/article/MED/42924773
AB - Background: Amelogenesis imperfecta affecting enamel formation is frequently associated with a variety of malocclusions and eruption disturbances. Orthodontic treatment is crucial in comprehensive patient management. Previous studies have shown that orthodontic treatment becomes more challenging in patients with AI as the defective enamel affects the bracket bonding, retention of appliances and treatment mechanics and often needs modified bonding protocols, pre-treatment restorative build-ups, skeletal anchorage and general multidisciplinary management. There is no evidence of the ideal orthodontic treatment yet; available evidence only consists of case reports and small observational studies that address specific aspects with no established consensus. Therefore, this narrative review aimed to critically examine the contemporaneous evidence on orthodontic assessment and treatment planning in AI patients, drawing on studies identified through a structured literature search. Materials and Methods: An electronic search of the literature was conducted in the PubMed, Scopus, and ScienceDirect databases. Out of 640 records that were initially identified, 11 studies met the inclusion criteria for qualitative synthesis. Results: Bonding issues resulting from enamel defects tend to be identified as a significant clinical challenge necessitating modified orthodontic techniques. The included studies demonstrated that by using individualized treatment planning, modified bonding procedures, fixed appliances, expansion procedures, skeletal anchorage and combined orthognathic surgery in some cases within the multidisciplinary treatment approach, there can be successful orthodontic management for these patients. Conclusions: Vital steps such as early diagnosis, careful treatment planning, and coordination with restorative and prosthodontic treatment were associated with better functional and esthetic outcomes. Consequently, even though there is limited evidence, the available literature supports a customized interdisciplinary approach as the most predictable and effective strategy for managing orthodontic problems in patients with AI, while emphasizing that case reports and small observational studies are the main sources of current findings.
SN - 2571-841X
ER -