Peer-reviewedCC BY-NC-SA 4.0Annals of African Medicine30 Jun 2026

Rare Fatal Event of Multidrug-resistant Shigella Septicemia and Cryptococcal Meningitis in an Immunocompromised Host

Sunandini Kapoor¹
Rajat Prakash¹
Saranya Datta¹
Iva Chandola¹
Ashutosh Bhatt²
Kanica Rawat³

¹Department of Microbiology, Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, Uttarakhand, India
²Department of General Medicine, Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, Uttarakhand, India
³Department of Radio-diagnosis, Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, Uttarakhand, India

Abstract

Bacteriemia due to Shigella spp. is a rare event. However, an individual with impaired immunity remains at risk of such invasion where the infective dose is as low as 10 viable bacilli. This case report describes one such fatal event where a 40-year-old immunocompromised male presented to a tertiary-level healthcare facility with a history of diarrhea for 10 days and seizures. Prompt microbiological workup established multidrug-resistant Shigella flexneri septicemia and cryptococcal meningitis.

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BibTeX RIS

BibTeX

@article{kapoor2026rare,
  title = {{Rare Fatal Event of Multidrug-resistant Shigella Septicemia and Cryptococcal Meningitis in an Immunocompromised Host}},
  author = {Sunandini Kapoor and Rajat Prakash and Saranya Datta and Iva Chandola and Ashutosh Bhatt and Kanica Rawat},
  journal = {Annals of African Medicine},
  year = {2026},
  month = jun,
  doi = {10.4103/aam.aam_140_26},
  url = {https://doi.org/10.4103/aam.aam_140_26},
  note = {CC BY-NC-SA 4.0},
}

RIS

TY  - JOUR
TI  - Rare Fatal Event of Multidrug-resistant Shigella Septicemia and Cryptococcal Meningitis in an Immunocompromised Host
AU  - Sunandini Kapoor
AU  - Rajat Prakash
AU  - Saranya Datta
AU  - Iva Chandola
AU  - Ashutosh Bhatt
AU  - Kanica Rawat
PY  - 2026
DA  - 2026/06/30
JO  - Annals of African Medicine
DO  - 10.4103/aam.aam_140_26
UR  - https://doi.org/10.4103/aam.aam_140_26
AB  - Bacteriemia due to Shigella spp. is a rare event. However, an individual with impaired immunity remains at risk of such invasion where the infective dose is as low as 10 viable bacilli. This case report describes one such fatal event where a 40-year-old immunocompromised male presented to a tertiary-level healthcare facility with a history of diarrhea for 10 days and seizures. Prompt microbiological workup established multidrug-resistant Shigella flexneri septicemia and cryptococcal meningitis.
SN  - 1596-3519
SN  - 0975-5764
ER  -

Abstract

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