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PreprintCC BYmedRxiv

Incidence and factors associated with infections in kidney transplant recipients at the tertiary hospital, Thailand.

  1. 1College of Pharmacy, Rangsit University, Muang, Pathum thani, Thailand 12000

Abstract

In medical practice, the rising prevalence of infections in kidney transplant recipients (KTRs) is a notable concern. However, understanding the incidence and risk factors associated with infections in KTRs remains limited. This study aims to assess the incidence and factors associated infection among KTRs. Additionally, we also investigate the median time of each infection among KTRs.

A retrospective cohort study was conducted from 1 January 2018-31 December 2022 at Thailands tertiary hospital. We performed univariable and multivariable logistic regression analyses to identify potential risk factors related infection and investigated for the incidence and median time of each infection among KTRs.

A total of 179 participants were included in this study. Our findings reveal the kidney from living donor was protective factor for infection among KTRs (aOR 0.063, 95% CI 0.005-0.792; p = 0.032). Urinary tract infections (UTIs)showed as the predominant pathogenic manifestation among KTRs (43%). The median time of UTIs, cytomegalovirus (CMV) infection and pneumocystis pneumonia (PCP) were 16, 57 and 94.5 days, respectively.

Our study establishes that receiving a kidney from a living donor is a protective factor against post-kidney transplant infections. Particularly urinary tract infections were most common of infection. Monitoring urinary tract infections post-transplantation is recommended. Moreover, awareness of UTI, CMV infection and PCP should be concerned during 2-3 months after transplantation. However, due to a small sample size; we recommend to increase the number of particular participants in further investigations.

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BibTeX
@misc{phacharoen2026incidence,
  title = {{Incidence and factors associated with infections in kidney transplant recipients at the tertiary hospital, Thailand.}},
  author = {S. Phacharoen and A. Prawang and S. Kanchanasurakit and K. Phonphok and D. Duangrithi and P. Petchcharee and W. Sangsanit and R. Jintasataporn},
  howpublished = {medRxiv},
  year = {2026},
  month = sep,
  doi = {10.64898/2026.09.28.26364156},
  url = {https://www.medrxiv.org/content/10.64898/2026.09.28.26364156v1},
  note = {CC BY},
}
RIS
TY  - UNPB
TI  - Incidence and factors associated with infections in kidney transplant recipients at the tertiary hospital, Thailand.
AU  - S. Phacharoen
AU  - A. Prawang
AU  - S. Kanchanasurakit
AU  - K. Phonphok
AU  - D. Duangrithi
AU  - P. Petchcharee
AU  - W. Sangsanit
AU  - R. Jintasataporn
PY  - 2026
DA  - 2026/09/28
PB  - medRxiv
DO  - 10.64898/2026.09.28.26364156
UR  - https://www.medrxiv.org/content/10.64898/2026.09.28.26364156v1
AB  - In medical practice, the rising prevalence of infections in kidney transplant recipients (KTRs) is a notable concern. However, understanding the incidence and risk factors associated with infections in KTRs remains limited. This study aims to assess the incidence and factors associated infection among KTRs. Additionally, we also investigate the median time of each infection among KTRs.  A retrospective cohort study was conducted from 1 January 2018-31 December 2022 at Thailands tertiary hospital. We performed univariable and multivariable logistic regression analyses to identify potential risk factors related infection and investigated for the incidence and median time of each infection among KTRs.  A total of 179 participants were included in this study. Our findings reveal the kidney from living donor was protective factor for infection among KTRs (aOR 0.063, 95% CI 0.005-0.792; p = 0.032). Urinary tract infections (UTIs)showed as the predominant pathogenic manifestation among KTRs (43%). The median time of UTIs, cytomegalovirus (CMV) infection and pneumocystis pneumonia (PCP) were 16, 57 and 94.5 days, respectively.  Our study establishes that receiving a kidney from a living donor is a protective factor against post-kidney transplant infections. Particularly urinary tract infections were most common of infection. Monitoring urinary tract infections post-transplantation is recommended. Moreover, awareness of UTI, CMV infection and PCP should be concerned during 2-3 months after transplantation. However, due to a small sample size; we recommend to increase the number of particular participants in further investigations.
ER  -