Coupled neuro-fluid dynamics in human bioelectromagnetism
- 1Department of Psychology, University of Konstanz, Konstnaz, Germany
Abstract
Electroencephalography (EEG) and magnetoencephalography (MEG) are widely interpreted as direct, non-invasive measures of neural population activity, assuming surrounding tissue and cerebrospinal fluid (CSF) act as passive volume conductors that distorts but do not contribute to signal generation. Using conductive-fluid phantom experiments, structural magnetic resonance imaging, and in vivo EEG and MEG recordings, the present report challenges this assumption. Mechanically driven conductive fluid generated structured, oscillatory, source-localizable electromagnetic signals resembling M/EEG in the absence of neural tissue, and interindividual differences in CSF volume systematically moderated M/EEG signal amplitude. These findings suggest that, at the scales accessed by invasive and non-invasive electrophysiology, electromagnetic and mechanical processes form a coupled system in which contributions of neural currents and fluid motion cannot readily be uniquely separated.
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BibTeX
@misc{popov2026coupled,
title = {{Coupled neuro-fluid dynamics in human bioelectromagnetism}},
author = {T. Popov and G. A. Miller},
howpublished = {bioRxiv},
year = {2026},
month = oct,
doi = {10.64898/2026.10.08.757789},
url = {https://www.biorxiv.org/content/10.64898/2026.10.08.757789v1},
note = {CC BY-NC-ND},
}
RIS
TY - UNPB
TI - Coupled neuro-fluid dynamics in human bioelectromagnetism
AU - T. Popov
AU - G. A. Miller
PY - 2026
DA - 2026/10/08
PB - bioRxiv
DO - 10.64898/2026.10.08.757789
UR - https://www.biorxiv.org/content/10.64898/2026.10.08.757789v1
AB - Electroencephalography (EEG) and magnetoencephalography (MEG) are widely interpreted as direct, non-invasive measures of neural population activity, assuming surrounding tissue and cerebrospinal fluid (CSF) act as passive volume conductors that distorts but do not contribute to signal generation. Using conductive-fluid phantom experiments, structural magnetic resonance imaging, and in vivo EEG and MEG recordings, the present report challenges this assumption. Mechanically driven conductive fluid generated structured, oscillatory, source-localizable electromagnetic signals resembling M/EEG in the absence of neural tissue, and interindividual differences in CSF volume systematically moderated M/EEG signal amplitude. These findings suggest that, at the scales accessed by invasive and non-invasive electrophysiology, electromagnetic and mechanical processes form a coupled system in which contributions of neural currents and fluid motion cannot readily be uniquely separated.
ER -