Skip to content
DraconiticResearch
Search Sources API
184,584 studies31 sourcesUpdated 37 min ago
Peer-reviewedCC BY-NCAnnals of medicine

Acetabular osteophyte-like ossification in DDH: association with labral morphology and age.

  • Wei Yu1,2,3,4,5
  • Xiang Cheng1,2,3,4,5
  • Huimin Chen1,2,3,4,5
  • Lu Zhang1,2,3,4,5
  • Luoyou Zhou1,2,3,4,5
  • Yuxi Su3,4,5,6,7
  • Chuan Feng1,2,3,4,5
7 affiliations
  1. 1Radiology Department, Children's Hospital of Chongqing Medical University, Chongqing, China.
  2. 2Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, Chongqing, China.
  3. 3Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.
  4. 4National Clinical Research Center for Children and Adolescents' Health and Diseases, Chongqing, China.
  5. 5China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, China.
  6. 6Orthopedics Department, Children's Hospital of Chongqing Medical University, Chongqing, China.
  7. 7Chongqing Key Laboratory of Pediatrics, Chongqing, China.
Read full textPDFDOICite

Abstract

Background

Developmental dysplasia of the hip (DDH) is a common pediatric condition. The labrum-acetabular cartilage complex (LACC) undergoes morphological changes, but its relationship with acetabular osteophyte-like ossification (AOO) remains unclear. Purpose: To investigate the associations of AOO with LACC morphology and age.Purposes

To investigate the associations of AOO with LACC morphology and age.Patients and methods

We retrospectively reviewed preoperative pelvic radiographs, MRI, and CT images of 180 patients (199 hips) with DDH from January 2015 to December 2022. Acetabular index (AI) and Tönnis grade were assessed on radiographs, LACC morphology classified on MRI, and AOO identified on multiplanar CT reconstructions. Group comparisons, multivariable logistic regression, interaction analysis, and ROC analysis were performed.Results

AOO occurred in 44/146 (30.1%) inverted and 10/53 (18.9%) everted hips. In children >2 years, AOO was more frequent in the inverted group (p = 0.031), whereas no difference was found in those ≤2 years (p = 0.515). Multivariable analysis showed age was the most consistent independent correlate of AOO in the overall cohort (OR=1.022, p < 0.001). LACC morphology was not significant in the full model but became significant after excluding AI (OR=3.792, p = 0.012). In children >2 years, inverted LACC was independently associated with AOO (OR=7.66, p = 0.008), with a significant age-by-LACC interaction (p = 0.042). Age predicted AOO in both LACC groups (AUC 0.800 and 0.735). AOO predominantly involved the posterior acetabulum.Conclusion

Age was the most consistent independent correlate of AOO, while the effect of LACC morphology was age-dependent. Inverted LACC was strongly associated with AOO in children >2 years with a posterior predilection. These exploratory and hypothesis-generating findings require prospective validation.Level of evidence

III.

Related

  1. Open‐Source and Commercial 3‐Dimensional Computed Tomography Methods Show Limited Agreement for Classifying Acetabular Morphology in Patients Undergoing Hip Arthroscopy
    Ashley A. Ellingwood, Rajvarun S. Grewal, Henry M. Gass +7
    Arthroscopy, sports medicine, and rehabilitationPeer-reviewedCC BYFull textSurgery & anaesthesiaEurope PMC
  2. The degeneration of uncovertebral joints on CT assessment and its association with postoperative heterotopic ossification in one- or two-level artificial cervical arthroplasty.
    Yi Yang, Weiyang Zhong
    Frontiers in surgeryPeer-reviewedCC BYFull textSurgery & anaesthesiaEurope PMC
  3. Association of S2 Alar–Iliac Versus S1-Only Fixation with Spinopelvic Mobility and Acetabular Component Orientation in Total Hip Arthroplasty: A Standing–Sitting EOS Study
    Burak Abay, Meric Enercan, Azmi Hamzaoglu
    Journal of Clinical MedicinePeer-reviewedCC BY 4.0Surgery & anaesthesiaCrossref
  4. Posterior Osteophyte Resection from the Medial Femoral Condyle Increases Medial Gap of Extension and Mid-Flexion in Total Knee Arthroplasty
    Ji Hyun Ahn, Ki-Tae Park
    Clinics in orthopedic surgeryPeer-reviewedCC BY-NCFull textSurgery & anaesthesiaEurope PMC
  5. Progression of Macular Tissue Loss in Choroideremia and Its Association with Baseline Fundus Autofluorescence Morphology
    Shinichiro Chujo, Rouzbeh Abbasgholizadeh, Mai Alhelaly +12
    Ophthalmology sciencePeer-reviewedCC BY-NC-NDFull textGeneral medicineEurope PMC

Cite

BibTeXRIS
BibTeX
@article{yu2026acetabular,
  title = {{Acetabular osteophyte-like ossification in DDH: association with labral morphology and age.}},
  author = {Wei Yu and Xiang Cheng and Huimin Chen and Lu Zhang and Luoyou Zhou and Yuxi Su and Chuan Feng},
  journal = {Annals of medicine},
  year = {2026},
  month = oct,
  doi = {10.1080/07853890.2026.2724165},
  url = {https://europepmc.org/article/MED/42954256},
  note = {CC BY-NC},
}
RIS
TY  - JOUR
TI  - Acetabular osteophyte-like ossification in DDH: association with labral morphology and age.
AU  - Wei Yu
AU  - Xiang Cheng
AU  - Huimin Chen
AU  - Lu Zhang
AU  - Luoyou Zhou
AU  - Yuxi Su
AU  - Chuan Feng
PY  - 2026
DA  - 2026/10/29
JO  - Annals of medicine
DO  - 10.1080/07853890.2026.2724165
UR  - https://europepmc.org/article/MED/42954256
AB  - Background  Developmental dysplasia of the hip (DDH) is a common pediatric condition. The labrum-acetabular cartilage complex (LACC) undergoes morphological changes, but its relationship with acetabular osteophyte-like ossification (AOO) remains unclear. Purpose: To investigate the associations of AOO with LACC morphology and age.Purposes  To investigate the associations of AOO with LACC morphology and age.Patients and methods  We retrospectively reviewed preoperative pelvic radiographs, MRI, and CT images of 180 patients (199 hips) with DDH from January 2015 to December 2022. Acetabular index (AI) and Tönnis grade were assessed on radiographs, LACC morphology classified on MRI, and AOO identified on multiplanar CT reconstructions. Group comparisons, multivariable logistic regression, interaction analysis, and ROC analysis were performed.Results  AOO occurred in 44/146 (30.1%) inverted and 10/53 (18.9%) everted hips. In children >2 years, AOO was more frequent in the inverted group (p = 0.031), whereas no difference was found in those ≤2 years (p = 0.515). Multivariable analysis showed age was the most consistent independent correlate of AOO in the overall cohort (OR=1.022, p < 0.001). LACC morphology was not significant in the full model but became significant after excluding AI (OR=3.792, p = 0.012). In children >2 years, inverted LACC was independently associated with AOO (OR=7.66, p = 0.008), with a significant age-by-LACC interaction (p = 0.042). Age predicted AOO in both LACC groups (AUC 0.800 and 0.735). AOO predominantly involved the posterior acetabulum.Conclusion  Age was the most consistent independent correlate of AOO, while the effect of LACC morphology was age-dependent. Inverted LACC was strongly associated with AOO in children >2 years with a posterior predilection. These exploratory and hypothesis-generating findings require prospective validation.Level of evidence  III.
SN  - 0785-3890
SN  - 1365-2060
ER  -