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Peer-reviewedCC BY 4.0Frontiers in Transplantation

A dietary approach to skin cancer prevention in solid organ transplant recipients

  • Kerry Yang1
  • Melody Li2
  • Taylor Skinner3
  • Danlin Zeng4
  • Gabriela Sosa1
  • Jing Yi Han1
  • Fatemeh Jafarian5
5 affiliations
  1. 1Cumming School of Medicine, University of Calgary, Calgary, AB, Canada
  2. 2Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, Canada
  3. 3Discipline of Medicine, Memorial University of Newfoundland, St John’s, NL, Canada
  4. 4Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada
  5. 5Division of Dermatology, Department of Medicine, University of Calgary, Calgary, AB, Canada
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Abstract

Among all patient populations, solid organ transplant recipients are one of the most at-risk groups for cutaneous malignancies. While modern post-transplant treatment approaches have significantly improved life expectancy, these chronic immunosuppressive regimens often lead to the rapid proliferation of skin cancers such as squamous cell carcinoma, basal cell carcinoma, and melanoma. Despite advances in surveillance, photoprotection, and therapeutic strategies, there is still substantial morbidity and mortality due to cutaneous malignancies in transplant recipients. One potential low-risk approach to chemoprevention is through the diet. To gain a better understanding of skin cancer prevention using dietary compounds, a review of the current literature was conducted. By appraising the current evidence, there appears to be potential therapeutic benefit for a variety of different diets and nutritional compounds, including but not limited to the Mediterranean diet, omega-3 fatty acids, nicotinamide, and phytochemicals like polyphenols and carotenoids. Although significant knowledge gaps remain, dietary modification and supplementation could be a potentially effective approach to cutaneous chemoprevention among solid organ transplant recipients.

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Cite

BibTeXRIS
BibTeX
@article{yang2026dietary,
  title = {{A dietary approach to skin cancer prevention in solid organ transplant recipients}},
  author = {Kerry Yang and Melody Li and Taylor Skinner and Danlin Zeng and Gabriela Sosa and Jing Yi Han and Fatemeh Jafarian},
  journal = {Frontiers in Transplantation},
  year = {2026},
  month = oct,
  doi = {10.3389/frtra.2026.1949295},
  url = {https://doi.org/10.3389/frtra.2026.1949295},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - A dietary approach to skin cancer prevention in solid organ transplant recipients
AU  - Kerry Yang
AU  - Melody Li
AU  - Taylor Skinner
AU  - Danlin Zeng
AU  - Gabriela Sosa
AU  - Jing Yi Han
AU  - Fatemeh Jafarian
PY  - 2026
DA  - 2026/10/21
JO  - Frontiers in Transplantation
DO  - 10.3389/frtra.2026.1949295
UR  - https://doi.org/10.3389/frtra.2026.1949295
AB  - Among all patient populations, solid organ transplant recipients are one of the most at-risk groups for cutaneous malignancies. While modern post-transplant treatment approaches have significantly improved life expectancy, these chronic immunosuppressive regimens often lead to the rapid proliferation of skin cancers such as squamous cell carcinoma, basal cell carcinoma, and melanoma. Despite advances in surveillance, photoprotection, and therapeutic strategies, there is still substantial morbidity and mortality due to cutaneous malignancies in transplant recipients. One potential low-risk approach to chemoprevention is through the diet. To gain a better understanding of skin cancer prevention using dietary compounds, a review of the current literature was conducted. By appraising the current evidence, there appears to be potential therapeutic benefit for a variety of different diets and nutritional compounds, including but not limited to the Mediterranean diet, omega-3 fatty acids, nicotinamide, and phytochemicals like polyphenols and carotenoids. Although significant knowledge gaps remain, dietary modification and supplementation could be a potentially effective approach to cutaneous chemoprevention among solid organ transplant recipients.
SN  - 2813-2440
ER  -