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Peer-reviewedCC BY-NCPatient preference and adherence

Knowledge, Attitude and Practice Survey of Hospitalized Patients on Causes and Prevention of Deep Venous Thrombosis: A Cross-Sectional Study Using Structural Equation Modeling.

  1. 1Department of Vascular Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.

Abstract

Purpose

To assess hospitalized patients' knowledge, attitudes, and practices (KAP) regarding deep venous thrombosis (DVT) causes and prevention.Patients and methods

A cross-sectional survey was conducted at the Second Affiliated Hospital of Chongqing Medical University between March 1 and May 30, 2024. Self-developed questionnaires were used to collect demographic data and KAP from hospitalized patients. Multivariable logistic regression and structural equation modeling (SEM) were utilized to evaluate associated factors and mediating pathways. KAP scores were categorized into three levels: good (>75% of the range; K: >12; A, P: >40), moderate (50-75% of the range; K: 8-12; A:30-40, P: 30-40), and poor (≤50% of the range; K: ≤8; A:30-40, P: ≤30).Results

A total of 567 valid questionnaires were analyzed. Most patients had not received relevant education on DVT (68.6%). The mean (SD) scores were 5.88 (2.32) for knowledge, 40.06 (7.18) for attitude, and 32.53 (9.22) for practice. Many participants were uncertain about DVT's definition, etiology, symptoms, and preventive measures (31.0% to 54.0%). Eighty-four percent believed DVT prevention requires cooperation between medical staff, patients, and families. Eighty-one percent preferred oral anticoagulants. Thirty-seven percent monitored DVT symptoms regularly, and thirty-three percent learned about DVT from medical staff. Multivariate analysis showed that knowledge (OR=1.293, P<0.001) and attitude (OR=1.031, P=0.046) were protective factors positively associated with practice. Smoking (OR=0.601, P=0.026), no history of thrombosis (OR=0.292, P=0.003), and lack of education (OR=0.448, P=0.007) were independently associated with non-adherence, acting as independent risk factors for poor preventive practices. SEM results showed direct (β= (0.306, P=<0.001) and indirect effects of knowledge on practice (β=0.073, P=0.007).Conclusion

Hospitalized patients showed poor knowledge, positive attitudes, and moderate practices towards DVT. Targeted educational interventions are needed to improve their KAP regarding DVT.

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BibTeX
@article{wang2026knowledge,
  title = {{Knowledge, Attitude and Practice Survey of Hospitalized Patients on Causes and Prevention of Deep Venous Thrombosis: A Cross-Sectional Study Using Structural Equation Modeling.}},
  author = {Fei Wang and Wu Yu},
  journal = {Patient preference and adherence},
  year = {2026},
  month = oct,
  doi = {10.2147/ppa.s611410},
  url = {https://europepmc.org/article/MED/42974477},
  note = {CC BY-NC},
}
RIS
TY  - JOUR
TI  - Knowledge, Attitude and Practice Survey of Hospitalized Patients on Causes and Prevention of Deep Venous Thrombosis: A Cross-Sectional Study Using Structural Equation Modeling.
AU  - Fei Wang
AU  - Wu Yu
PY  - 2026
DA  - 2026/10/29
JO  - Patient preference and adherence
DO  - 10.2147/ppa.s611410
UR  - https://europepmc.org/article/MED/42974477
AB  - Purpose  To assess hospitalized patients' knowledge, attitudes, and practices (KAP) regarding deep venous thrombosis (DVT) causes and prevention.Patients and methods  A cross-sectional survey was conducted at the Second Affiliated Hospital of Chongqing Medical University between March 1 and May 30, 2024. Self-developed questionnaires were used to collect demographic data and KAP from hospitalized patients. Multivariable logistic regression and structural equation modeling (SEM) were utilized to evaluate associated factors and mediating pathways. KAP scores were categorized into three levels: good (>75% of the range; K: >12; A, P: >40), moderate (50-75% of the range; K: 8-12; A:30-40, P: 30-40), and poor (≤50% of the range; K: ≤8; A:30-40, P: ≤30).Results  A total of 567 valid questionnaires were analyzed. Most patients had not received relevant education on DVT (68.6%). The mean (SD) scores were 5.88 (2.32) for knowledge, 40.06 (7.18) for attitude, and 32.53 (9.22) for practice. Many participants were uncertain about DVT's definition, etiology, symptoms, and preventive measures (31.0% to 54.0%). Eighty-four percent believed DVT prevention requires cooperation between medical staff, patients, and families. Eighty-one percent preferred oral anticoagulants. Thirty-seven percent monitored DVT symptoms regularly, and thirty-three percent learned about DVT from medical staff. Multivariate analysis showed that knowledge (OR=1.293, P<0.001) and attitude (OR=1.031, P=0.046) were protective factors positively associated with practice. Smoking (OR=0.601, P=0.026), no history of thrombosis (OR=0.292, P=0.003), and lack of education (OR=0.448, P=0.007) were independently associated with non-adherence, acting as independent risk factors for poor preventive practices. SEM results showed direct (β= (0.306, P=<0.001) and indirect effects of knowledge on practice (β=0.073, P=0.007).Conclusion  Hospitalized patients showed poor knowledge, positive attitudes, and moderate practices towards DVT. Targeted educational interventions are needed to improve their KAP regarding DVT.
SN  - 1177-889X
ER  -