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Peer-reviewedCC BYJournal for ImmunoTherapy of Cancer

942 cDC1-independent tumor rejection: CD45-targeted IL-12 reveals a cDC2–CD4+ T cell axis as a driver of lung tumor immunity

  • Robert Langer1
  • Stefani Spranger2
  • Vidit Bhandarkar3
  • Sean-Luc Shanahan3
  • Tyler Jacks4
  • Molly Carney5
  • Brett H Pogostin1
  • Taylor Heim1
  • Ana Jaklenec1
  • Darrell J Irvine6
6 affiliations
  1. 1Massachusetts Institute of Technology, Cambridge, MA, USA
  2. 23Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA, USA
  3. 31Massachusetts Institute of Technology, Cambridge, MA, USA
  4. 4Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA, USA
  5. 51Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA, USA
  6. 6The Scripps Research Institute, La Jolla, CA, USA
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Cite

BibTeXRIS
BibTeX
@article{langer2026cdc1independent,
  title = {{942 cDC1-independent tumor rejection: CD45-targeted IL-12 reveals a cDC2–CD4+ T cell axis as a driver of lung tumor immunity}},
  author = {Robert Langer and Stefani Spranger and Vidit Bhandarkar and Sean-Luc Shanahan and Tyler Jacks and Molly Carney and Brett H Pogostin and Taylor Heim and Ana Jaklenec and Darrell J Irvine},
  journal = {Journal for ImmunoTherapy of Cancer},
  year = {2026},
  month = nov,
  doi = {10.1136/jitc-2026-sitc2026.0942},
  url = {https://doi.org/10.1136/jitc-2026-sitc2026.0942},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - 942 cDC1-independent tumor rejection: CD45-targeted IL-12 reveals a cDC2–CD4+ T cell axis as a driver of lung tumor immunity
AU  - Robert Langer
AU  - Stefani Spranger
AU  - Vidit Bhandarkar
AU  - Sean-Luc Shanahan
AU  - Tyler Jacks
AU  - Molly Carney
AU  - Brett H Pogostin
AU  - Taylor Heim
AU  - Ana Jaklenec
AU  - Darrell J Irvine
PY  - 2026
DA  - 2026/11/07
JO  - Journal for ImmunoTherapy of Cancer
DO  - 10.1136/jitc-2026-sitc2026.0942
UR  - https://doi.org/10.1136/jitc-2026-sitc2026.0942
SN  - 2051-1426
ER  -