Dietary Patterns and Cardiovascular Risk in Adult Survivors of Childhood Cancer: Findings From the SCCSS-Nutrition Study
- 1ISPM Unibe
Abstract
PurposeTo identify dietary patterns among adult childhood cancer survivors (CCSs), examine their determinants, and assess whether they differ according to cardiovascular disease (CVD) risk profiles.
MethodsCCSs from the Swiss Childhood Cancer Survivor Study diagnosed before age 21 years (1976-2005), surviving [≥]5 years and aged [≥]18 years in 2017, completed a food frequency questionnaire (SCCSS-Nutrition). Factor and hierarchical cluster analyses of 52 food groups identified dietary patterns. We categorised CCSs as having CVD, CVD risk factors (obesity, hypertension, diabetes, high cholesterol), or being CVD risk-free. Multinomial logistic regression assessed associations between dietary patterns and CVD risk profiles.
ResultsAmong 802 CCSs (median age: 35 years; IQR: 29-41; 50% male), we identified five dietary patterns: Mediterranean-inspired diet (22%), Western indulgence diet (38%), Western sweet & fatty diet (26%), restrained indulgence diet (9%), plant-based & alcohol-rich diet (6%). Male sex, younger age, German-speaking region, smoking, and living with others were associated with Western indulgence, Western sweet & fatty, and restrained indulgence diets. Higher Swiss socioeconomic position (Swiss-SEP) and education, and not having children, were associated with the plant-based & alcohol-rich diet, higher Swiss-SEP was also associated with the Western indulgence diet. No associations were observed between dietary patterns and CVD risk profiles.
ConclusionsDietary patterns among adult CCSs were socially patterned and differed according to sociodemographic and lifestyle characteristics, but were not associated with CVD risk profiles.
Implications for Cancer SurvivorsDietary counselling and broader lifestyle support should be considered as part of long-term survivorship care for CCSs.
Related
- Association of Care Coordination and Discontinuity With Patterns of Care and Outcomes in Childhood Cancer Survivors With Multiple Chronic Conditions: A Report From the Childhood Cancer Survivor Study
- Gendered patterns of reporting childhood abuse and quality of parental relationships across 21 nations: Descriptive findings from the Global Flourishing Study (GFS)
- Historical Baseline Electrocardiogram Ascertainment Prior to Cancer Diagnosis and Cardiovascular Diagnosis Patterns in Cancer Survivors: A Retrospective Observational Cohort Study
- Body mass index change patterns and risk of hospitalization among populations at high cardiovascular risk: findings from the China PEACE Million Persons Project
- Real-life Psychological Experiences and Subsequent Cardiovascular Events among Survivors of a Myocardial Infarction in Midlife: Prospective Cohort Study
BibTeX
@misc{li2026dietary,
title = {{Dietary Patterns and Cardiovascular Risk in Adult Survivors of Childhood Cancer: Findings From the SCCSS-Nutrition Study}},
author = {R. Li and R. Revuelta Iniesta and A. R. Barker and A. Chatelan and L. M. Leuenberger and Y. Shoman and B. D. Spycher and F. N. Belle},
howpublished = {medRxiv},
year = {2026},
month = sep,
doi = {10.64898/2026.09.22.26363621},
url = {https://www.medrxiv.org/content/10.64898/2026.09.22.26363621v1},
note = {CC BY},
}
RIS
TY - UNPB
TI - Dietary Patterns and Cardiovascular Risk in Adult Survivors of Childhood Cancer: Findings From the SCCSS-Nutrition Study
AU - R. Li
AU - R. Revuelta Iniesta
AU - A. R. Barker
AU - A. Chatelan
AU - L. M. Leuenberger
AU - Y. Shoman
AU - B. D. Spycher
AU - F. N. Belle
PY - 2026
DA - 2026/09/22
PB - medRxiv
DO - 10.64898/2026.09.22.26363621
UR - https://www.medrxiv.org/content/10.64898/2026.09.22.26363621v1
AB - PurposeTo identify dietary patterns among adult childhood cancer survivors (CCSs), examine their determinants, and assess whether they differ according to cardiovascular disease (CVD) risk profiles. MethodsCCSs from the Swiss Childhood Cancer Survivor Study diagnosed before age 21 years (1976-2005), surviving [≥]5 years and aged [≥]18 years in 2017, completed a food frequency questionnaire (SCCSS-Nutrition). Factor and hierarchical cluster analyses of 52 food groups identified dietary patterns. We categorised CCSs as having CVD, CVD risk factors (obesity, hypertension, diabetes, high cholesterol), or being CVD risk-free. Multinomial logistic regression assessed associations between dietary patterns and CVD risk profiles. ResultsAmong 802 CCSs (median age: 35 years; IQR: 29-41; 50% male), we identified five dietary patterns: Mediterranean-inspired diet (22%), Western indulgence diet (38%), Western sweet & fatty diet (26%), restrained indulgence diet (9%), plant-based & alcohol-rich diet (6%). Male sex, younger age, German-speaking region, smoking, and living with others were associated with Western indulgence, Western sweet & fatty, and restrained indulgence diets. Higher Swiss socioeconomic position (Swiss-SEP) and education, and not having children, were associated with the plant-based & alcohol-rich diet, higher Swiss-SEP was also associated with the Western indulgence diet. No associations were observed between dietary patterns and CVD risk profiles. ConclusionsDietary patterns among adult CCSs were socially patterned and differed according to sociodemographic and lifestyle characteristics, but were not associated with CVD risk profiles. Implications for Cancer SurvivorsDietary counselling and broader lifestyle support should be considered as part of long-term survivorship care for CCSs.
ER -