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Peer-reviewedCC BYAdvanced science (Weinheim, Baden-Wurttemberg, Germany)

Loss-Engineered Terahertz Pixelated Metasensors for Enhanced Molecular Vibrational Fingerprint Sensing.

  • Chenglin Yang1
  • Yuqing Cui1
  • Donghai Han1
  • Yushan Hou1
  • Zhonglei Shen2
  • Andreas Tittl3,4
  • Liuyang Zhang1
  • Ruqiang Yan1
  • Xuefeng Chen1
4 affiliations
  1. 1School of Mechanical Engineering, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
  2. 2Division of Physics and Applied Physics, Nanyang Technological University, Singapore, Singapore.
  3. 3Institute of Photonics, Hamburg University of Technology, Hamburg, Germany.
  4. 4Chair in Hybrid Nanosystems, Nanoinstitute Munich, Faculty of Physics, Ludwig-Maximilians-Universität München, Munich, Germany.
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Abstract

Molecular vibrational fingerprints in the terahertz (THz) regime offer unique opportunities for label-free chemical and biological sensing. Metasensors can amplify these vibrational signals through local near-field enhancement. However, current THz molecular fingerprint metasensors lack a systematic design and optimization methodology, which severely limits their potential. Here, we unveil the crucial role of resonant loss rate in THz molecular fingerprint sensing and present a loss-engineering methodology for optimized molecular vibrational sensing. Based on the proposed methodology, we experimentally demonstrate a 12.6-fold enhancement of the molecular fingerprint signal with three-dimensionally printed pixelated metasensors. Furthermore, the pixelated metasensors support vibrational strong-coupling, providing a unified platform for enhanced molecular sensing and strong light-matter interaction. Overall, the proposed metasensor could bridge THz molecular vibrational fingerprint sensing to end-use applications in label-free chemical and biomedical detection.

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Cite

BibTeXRIS
BibTeX
@article{yang2026lossengineered,
  title = {{Loss-Engineered Terahertz Pixelated Metasensors for Enhanced Molecular Vibrational Fingerprint Sensing.}},
  author = {Chenglin Yang and Yuqing Cui and Donghai Han and Yushan Hou and Zhonglei Shen and Andreas Tittl and Liuyang Zhang and Ruqiang Yan and Xuefeng Chen},
  journal = {Advanced science (Weinheim, Baden-Wurttemberg, Germany)},
  year = {2026},
  month = oct,
  doi = {10.1002/advs.78233},
  url = {https://europepmc.org/article/MED/42875704},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Loss-Engineered Terahertz Pixelated Metasensors for Enhanced Molecular Vibrational Fingerprint Sensing.
AU  - Chenglin Yang
AU  - Yuqing Cui
AU  - Donghai Han
AU  - Yushan Hou
AU  - Zhonglei Shen
AU  - Andreas Tittl
AU  - Liuyang Zhang
AU  - Ruqiang Yan
AU  - Xuefeng Chen
PY  - 2026
DA  - 2026/10/14
JO  - Advanced science (Weinheim, Baden-Wurttemberg, Germany)
DO  - 10.1002/advs.78233
UR  - https://europepmc.org/article/MED/42875704
AB  - Molecular vibrational fingerprints in the terahertz (THz) regime offer unique opportunities for label-free chemical and biological sensing. Metasensors can amplify these vibrational signals through local near-field enhancement. However, current THz molecular fingerprint metasensors lack a systematic design and optimization methodology, which severely limits their potential. Here, we unveil the crucial role of resonant loss rate in THz molecular fingerprint sensing and present a loss-engineering methodology for optimized molecular vibrational sensing. Based on the proposed methodology, we experimentally demonstrate a 12.6-fold enhancement of the molecular fingerprint signal with three-dimensionally printed pixelated metasensors. Furthermore, the pixelated metasensors support vibrational strong-coupling, providing a unified platform for enhanced molecular sensing and strong light-matter interaction. Overall, the proposed metasensor could bridge THz molecular vibrational fingerprint sensing to end-use applications in label-free chemical and biomedical detection.
SN  - 2198-3844
ER  -