Temporal trends and regional disparities in mortality from acute myocardial infarction in Brazil: a time series study, 2015-2024.
- 1Pontifícia Universidade Católica de Goiás, Medicina, Goiânia, GO, Brazil.
- 2Universidade Federal de Goiás, Enfermagem, Goiânia, GO, Brazil.
Abstract
Objective
To analyze mortality from acute myocardial infarction in Brazil according to temporal trends, sociodemographic characteristics, and regional disparities from 2015 to 2024.Methods
A time series study using annual aggregated data from the Mortality Information System (Sistema de Informações sobre Mortalidade, SIM). Unadjusted mortality rates, age-standardized mortality rates, and sex-specific rate ratios were calculated. Temporal trends were assessed using log-linear regression to estimate the annual percent change (APC), and reestimated using the Prais-Winsten method as a complementary analysis.Results
A total of 938,997 deaths were recorded during the study period. The absolute number of deaths remained stable, with a 3.8% increase between 2015 and 2024. Age-standardized mortality rates declined throughout the study period (annual percent change: -2.6%; p-value<0.001). Mortality was higher among males, with a mean rate ratio of 1.53 over the study period, reaching 1.58 in 2024, and was concentrated among older adults. The Southeast and Northeast regions had the highest unadjusted mortality rates.Conclusion
Age-standardized mortality rates declined over the study period, although the high burden of deaths associated with population aging and regional disparities persisted. These findings reinforce the need to strengthen cardiovascular disease prevention strategies, timely diagnosis, and the organization of the healthcare network for cardiovascular diseases within the Brazilian Unified Health System (Sistema Único de Saúde, SUS).
Related
- ECG-Derived Synthetic Left Ventricular Mechanics Predict Mortality After Acute Myocardial Infarction and Fatal Myocardial Infarction in the General Population
- The effect of regional disparities in access to rehabilitation services on mortality among stroke patients : A Korean nationwide population-based retrospective cohort study
- Factors associated with 30-day mortality in patients with post-myocardial infarction ventricular septal rupture: a retrospective cohort study
- Predictive value of combined estimated plasma volume status and neutrophil-to-lymphocyte ratio for cardiovascular mortality in patients with acute myocardial infarction with heart failure
- Comparative Associations of Inflammation and Nutrition-Based Indices with No-Reflow and Mortality After Primary PCI for ST-Elevation Myocardial Infarction
BibTeX
@article{silva2026temporal,
title = {{Temporal trends and regional disparities in mortality from acute myocardial infarction in Brazil: a time series study, 2015-2024.}},
author = {Geovanna Aires Silva and Carlos Henrique Santos and Jacqueline Andréia Bernardes Leão-Cordeiro and Antonio Marcio Teodoro Cordeiro Silva},
journal = {Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil},
year = {2026},
month = sep,
doi = {10.1590/s2237-96222026v35e20260533.en},
url = {https://europepmc.org/article/MED/42834884},
note = {CC BY},
}
RIS
TY - JOUR
TI - Temporal trends and regional disparities in mortality from acute myocardial infarction in Brazil: a time series study, 2015-2024.
AU - Geovanna Aires Silva
AU - Carlos Henrique Santos
AU - Jacqueline Andréia Bernardes Leão-Cordeiro
AU - Antonio Marcio Teodoro Cordeiro Silva
PY - 2026
DA - 2026/09/25
JO - Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil
DO - 10.1590/s2237-96222026v35e20260533.en
UR - https://europepmc.org/article/MED/42834884
AB - Objective To analyze mortality from acute myocardial infarction in Brazil according to temporal trends, sociodemographic characteristics, and regional disparities from 2015 to 2024.Methods A time series study using annual aggregated data from the Mortality Information System (Sistema de Informações sobre Mortalidade, SIM). Unadjusted mortality rates, age-standardized mortality rates, and sex-specific rate ratios were calculated. Temporal trends were assessed using log-linear regression to estimate the annual percent change (APC), and reestimated using the Prais-Winsten method as a complementary analysis.Results A total of 938,997 deaths were recorded during the study period. The absolute number of deaths remained stable, with a 3.8% increase between 2015 and 2024. Age-standardized mortality rates declined throughout the study period (annual percent change: -2.6%; p-value<0.001). Mortality was higher among males, with a mean rate ratio of 1.53 over the study period, reaching 1.58 in 2024, and was concentrated among older adults. The Southeast and Northeast regions had the highest unadjusted mortality rates.Conclusion Age-standardized mortality rates declined over the study period, although the high burden of deaths associated with population aging and regional disparities persisted. These findings reinforce the need to strengthen cardiovascular disease prevention strategies, timely diagnosis, and the organization of the healthcare network for cardiovascular diseases within the Brazilian Unified Health System (Sistema Único de Saúde, SUS).
SN - 1679-4974
SN - 2237-9622
ER -