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Peer-reviewedCC BY-NC-ND 4.0Cell Reports

Pharmacologically targeting CDK12 induces BRCAness and synergizes with merestinib to exacerbate DNA damage in high-risk neuroblastoma

  • Joshua Robert Goulding
  • Stijn Tim Couwenbergh
  • Sarah-Lee Bekaert
  • Ellen Sanders
  • Fanny De Vloed
  • Vicky Amo-Addae
  • Aline Eggermont
  • Jolien De Wyn
  • Kaat De Wever
  • Lasse Vleminckx
  • Selma Eising
  • Jan J. Molenaar
3 more authors
  • Marlinde L. van den Boogaard
  • Lisa Depestel
  • Kaat Durinck
Open at sourceDOICite

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Cite

BibTeXRIS
BibTeX
@article{goulding2026pharmacologically,
  title = {{Pharmacologically targeting CDK12 induces BRCAness and synergizes with merestinib to exacerbate DNA damage in high-risk neuroblastoma}},
  author = {Joshua Robert Goulding and Stijn Tim Couwenbergh and Sarah-Lee Bekaert and Ellen Sanders and Fanny De Vloed and Vicky Amo-Addae and Aline Eggermont and Jolien De Wyn and Kaat De Wever and Lasse Vleminckx and Selma Eising and Jan J. Molenaar and Marlinde L. van den Boogaard and Lisa Depestel and Kaat Durinck},
  journal = {Cell Reports},
  year = {2026},
  month = oct,
  doi = {10.1016/j.celrep.2026.117997},
  url = {https://linkinghub.elsevier.com/retrieve/pii/S2211124726010752},
  note = {CC BY-NC-ND 4.0},
}
RIS
TY  - JOUR
TI  - Pharmacologically targeting CDK12 induces BRCAness and synergizes with merestinib to exacerbate DNA damage in high-risk neuroblastoma
AU  - Joshua Robert Goulding
AU  - Stijn Tim Couwenbergh
AU  - Sarah-Lee Bekaert
AU  - Ellen Sanders
AU  - Fanny De Vloed
AU  - Vicky Amo-Addae
AU  - Aline Eggermont
AU  - Jolien De Wyn
AU  - Kaat De Wever
AU  - Lasse Vleminckx
AU  - Selma Eising
AU  - Jan J. Molenaar
AU  - Marlinde L. van den Boogaard
AU  - Lisa Depestel
AU  - Kaat Durinck
PY  - 2026
DA  - 2026/10/01
JO  - Cell Reports
DO  - 10.1016/j.celrep.2026.117997
UR  - https://linkinghub.elsevier.com/retrieve/pii/S2211124726010752
SN  - 2211-1247
ER  -