Skip to content
DraconiticResearch
Search Sources API
203,234 studies31 sourcesUpdated 1 h ago
Peer-reviewedCC BYFrontiers in oral health

Surgical repair of facial nerve defects by an autologous great auricular nerve transplantation: a retrospective, 12-month, follow-up study.

  • Huawei Liu1
  • Qi Ning1
  • Xiaodan Mu2
  • Wenting Bi3
  • Qingyan Sun1
  • Zhigang Cai4,5,6
  • Shijun Li5,6,7
  • Xiaofeng Shan4
  • Min Hu1
7 affiliations
  1. 1Department of Stomatology, The First Medical Center of PLA General Hospital, Beijing, China.
  2. 2Department of Stomatology, Beijing Friendship Hospital Affiliated to Capital Medical University, Beijing, China.
  3. 3Department of Stomatology, Beijing Hospital of Integrated Traditional Chinese and Western Medicine, Beijing, China.
  4. 4Department of Oral surgery, Peking University School and Hospital of Stomatology, Beijing, China.
  5. 5National Center of Stomatology, National Clinical Research Center for Oral Diseases, Beijing, China.
  6. 6National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China.
  7. 7First Clinical Division, Peking University School and Hospital of Stomatology, Beijing, China.
Read full textPDFDOICite

Abstract

Background

To observe facial nerve function recovery from an autologous great auricular nerve (GAN) transplantation in repairing facial nerve defects.Methods

Thirty-six patients were included. Facial nerve functions were evaluated by using the House-Brackmann grading system. Abnormal sensations after the GAN sacrifice were recorded.Results

The follow-up lasted for an average of 18.5 (12-60) months. Facial nerve defects were caused by parotid gland malignancies (n = 30) or trauma (n = 6), with an average length of 2.6 ± 1.1 (1.0-6.5) cm. One case showed tumor recurrence during the follow-up. Lack of feeling (78.1%) was the dominant postoperative abnormal sensation, followed by lack of sensitivity (53.1%) and abnormal sensation (40.6%). Long facial nerve defects (>3 cm) and preoperative facial paralysis combined with parotid gland malignancies retarded facial nerve function recovery.Conclusion

Autologous GAN transplantation is effective for repairing facial nerve defects and recovering facial nerve function during the 12-month follow-up period.

Related

  1. Surgical technique of nonvascularized rectus fascia transplantation for complex thoracic defects
    Margherita Brivio, Ewout Muylle, Guillaume Hendrickx +12
    JTCVS techniquesPeer-reviewedCC BY-NC-NDFull textGeneral medicineEurope PMC
  2. Healthcare resource utilisation and costs of chemotherapy and autologous haemopoietic cell transplantation of patients with multiple myeloma in China: a multi-centre retrospective analysis
    Yannan Wang, Ling Li, Peng Ji +4
    BMJ OpenPeer-reviewedCC BY-NC 4.0Full textGeneral medicineCrossref
  3. Injectable autologous chondrocyte transplantation yields sustained clinical mid‐term improvement in acetabular cartilage defects in femoroacetabular impingement: A comparative analysis from the German Cartilage Registry (KnorpelRegister DGOU)
    Moritz Riedl, Stefan Landgraeber, Steffen Thier +6
    Journal of experimental orthopaedicsPeer-reviewedCC BYFull textSurgery & anaesthesiaEurope PMCEurope PMCPMC
  4. Oral versus intravenous melphalan for autologous stem cell transplantation conditioning in lymphoma and multiple myeloma: a retrospective cohort study
    Jingrong Wang, Yimeng Guo, Jin Zhao +4
    Frontiers in OncologyPeer-reviewedCC BY 4.0Full textOncologyCrossrefEurope PMCPMCEurope PMC
  5. Efficacy and safety of air-flow beds for autologous hematopoietic stem cell transplantation in multiple myeloma: a retrospective cohort study
    Zhangbiao Long, Dinghui Zhao, Min Ruan +8
    Frontiers in oncologyPeer-reviewedCC BYFull textOncologyEurope PMCCrossref

Cite

BibTeXRIS
BibTeX
@article{liu2026surgical,
  title = {{Surgical repair of facial nerve defects by an autologous great auricular nerve transplantation: a retrospective, 12-month, follow-up study.}},
  author = {Huawei Liu and Qi Ning and Xiaodan Mu and Wenting Bi and Qingyan Sun and Zhigang Cai and Shijun Li and Xiaofeng Shan and Min Hu},
  journal = {Frontiers in oral health},
  year = {2026},
  month = oct,
  doi = {10.3389/froh.2026.1920749},
  url = {https://europepmc.org/article/MED/42898287},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Surgical repair of facial nerve defects by an autologous great auricular nerve transplantation: a retrospective, 12-month, follow-up study.
AU  - Huawei Liu
AU  - Qi Ning
AU  - Xiaodan Mu
AU  - Wenting Bi
AU  - Qingyan Sun
AU  - Zhigang Cai
AU  - Shijun Li
AU  - Xiaofeng Shan
AU  - Min Hu
PY  - 2026
DA  - 2026/10/05
JO  - Frontiers in oral health
DO  - 10.3389/froh.2026.1920749
UR  - https://europepmc.org/article/MED/42898287
AB  - Background  To observe facial nerve function recovery from an autologous great auricular nerve (GAN) transplantation in repairing facial nerve defects.Methods  Thirty-six patients were included. Facial nerve functions were evaluated by using the House-Brackmann grading system. Abnormal sensations after the GAN sacrifice were recorded.Results  The follow-up lasted for an average of 18.5 (12-60) months. Facial nerve defects were caused by parotid gland malignancies (n = 30) or trauma (n = 6), with an average length of 2.6 ± 1.1 (1.0-6.5) cm. One case showed tumor recurrence during the follow-up. Lack of feeling (78.1%) was the dominant postoperative abnormal sensation, followed by lack of sensitivity (53.1%) and abnormal sensation (40.6%). Long facial nerve defects (>3 cm) and preoperative facial paralysis combined with parotid gland malignancies retarded facial nerve function recovery.Conclusion  Autologous GAN transplantation is effective for repairing facial nerve defects and recovering facial nerve function during the 12-month follow-up period.
SN  - 2673-4842
ER  -