Peer-reviewedLicence not statedScience (New York, N.Y.)
Thalamic NRXN1-mediated input to human cortical progenitors drives excitatory neurogenesis
10 affiliations
- 1Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
- 2Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
- 3Genomics Institute, University of California Santa Cruz, Santa Cruz, CA, USA.
- 4Department of Molecular, Cellular and Developmental Biology, University of California Santa Cruz, Santa Cruz, CA, USA.
- 5Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, USA.
- 6Department of Neurology, University of Michigan, Ann Arbor, MI, USA.
- 7Michigan Neuroscience Institute, University of Michigan, Ann Arbor, MI, USA.
- 8VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.
- 9Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
- 10Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Related
- AAV-DJ enables efficient, function-preserving neuronal transduction for circuit interrogation in human cortical and thalamic organoids
- Multipotent radial glia sequentially deploy fate-restricted intermediate progenitors to diversify cortical interneurons
- Arhgef1 Deletion Disrupts Early Cortical Neurogenesis via PAK1 Overactivation and Causes Motor Dysfunction in Adulthood
- Reduction of forebrain interneurons alters cellular organization and cortical neurogenesis in a mouse model of X-linked intellectual disability
- Repeated morphine reorganizes sleep-wake states, cortical and central medial thalamic oscillations, and network synchronization in mice
BibTeX
@article{nguyen2026thalamic,
title = {{Thalamic NRXN1-mediated input to human cortical progenitors drives excitatory neurogenesis}},
author = {Claudia V. Nguyen and Antoni Martija and Daniel C. Jaklic and Rista White and Marty G. Yang and Patricia R. Nano and Jose A. Soto and Jessenya Mil and Dakshesh Rana and Jacqueline M. Martin and Hunter E. Schweiger and Sebastian Hernandez and Elisa Fazzari and Yu Liu and Jack M. Parent and Mohammed A. Mostajo-Radji and Daniel H. Geschwind and Aparna Bhaduri},
journal = {Science (New York, N.Y.)},
year = {2026},
month = sep,
doi = {10.1126/science.ady5180},
url = {https://doi.org/10.1126/science.ady5180},
}
RIS
TY - JOUR
TI - Thalamic NRXN1-mediated input to human cortical progenitors drives excitatory neurogenesis
AU - Claudia V. Nguyen
AU - Antoni Martija
AU - Daniel C. Jaklic
AU - Rista White
AU - Marty G. Yang
AU - Patricia R. Nano
AU - Jose A. Soto
AU - Jessenya Mil
AU - Dakshesh Rana
AU - Jacqueline M. Martin
AU - Hunter E. Schweiger
AU - Sebastian Hernandez
AU - Elisa Fazzari
AU - Yu Liu
AU - Jack M. Parent
AU - Mohammed A. Mostajo-Radji
AU - Daniel H. Geschwind
AU - Aparna Bhaduri
PY - 2026
DA - 2026/09/03
JO - Science (New York, N.Y.)
DO - 10.1126/science.ady5180
UR - https://doi.org/10.1126/science.ady5180
SN - 0036-8075
SN - 1095-9203
ER -