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Peer-reviewedLicence not statedBlood

Genomic drivers of leukemia and blinatumomab response in adult acute lymphoblastic leukemia – the ECOG-ACRIN E1910 study

  • Xiaoming Zhong1
  • Kathryn G. Roberts1
  • Huimei Wei2
  • Zhuoxin Sun3
  • Lindsey E. Montefiori2
  • Amit Kumar1
  • Ilaria Iacobucci2
  • Pradyumna Baviskar2
  • Qingsong Gao2
  • Petri Pölönen2
  • Shondra M. Pruett-Miller4
  • Rori M. Schreiber4
50 more authors
  • Ti-Cheng Chang5
  • Wenchao Zhang5
  • Shaohua Lei1
  • Evadnie Rampersaud5
  • Yiping Fan5
  • Gang Wu5
  • Ryan J. Mattison6
  • Yanming Zhang7
  • Janis Racevskis8
  • Hillard M. Lazarus9
  • Jacob M. Rowe10
  • Daniel A. Arber11
  • Matthew J. Wieduwilt12
  • Yasser A. Mourad13
  • Paul J. Shami14
  • Maria R. Baer15
  • Adam Asch16
  • Kristen M. O’Dwyer17
  • Aric Hall18
  • Michaela Liedtke19
  • Julie Bergeron20
  • Brent L. Wood21
  • Keith W. Pratz22
  • Shira N. Dinner23
  • Noelle Frey22
  • Steven D. Gore24
  • Bhavana Bhatnagar25
  • Ehab L. Atallah26
  • Geoffrey L. Uy27
  • Deepa Jeyakumar28
  • Tara L. Lin29
  • Cheryl L. Willman30
  • Nikolai Podoltsev31
  • Daniel J. DeAngelo3
  • Shejal B. Patel32
  • Michelle A. Elliot30
  • Anjali S. Advani33
  • Dimitrios Tzachanis34
  • Pankit Vachhani35
  • Rupali Roy Bhave12
  • Elad Sharon3
  • Richard F. Little24
  • Harry P. Erba36
  • Richard M. Stone3
  • Martin S. Tallman7
  • Jun J. Yang37
  • Selina M. Luger22
  • Elisabeth M. Paietta8

60 listed; 62 in total.

37 affiliations
  1. 1Center of Excellence for Leukemia Studies, St. Jude Children’s Research Hospital, Memphis TN, USA
  2. 2Department of Pathology, St. Jude Children’s Research Hospital, Memphis TN, USA
  3. 3Dana-Farber Cancer Institute, Boston MA, USA
  4. 4Center for Advanced Genome Engineering, Department of Cell and Molecular Biology, St. Jude Children’s Research Hospital, Memphis TN, USA
  5. 5Center for Applied Bioinformatics, St. Jude Children’s Research Hospital, Memphis TN, USA
  6. 6University of Wisconsin Carbone Cancer Center, Madison WI, USA
  7. 7Memorial Sloan Kettering Cancer Center, New York NY, USA
  8. 8Montefiore Medical Center Moses Campus, Bronx NY, USA
  9. 9Case Western Reserve University, Cleveland OH, USA
  10. 10Shaare Zedek Medical Center, Jerusalem, Israel
  11. 11University of Chicago, Chicago IL, USA
  12. 12Wake Forest University School of Medicine, Winston-Salem NC, USA
  13. 13The University of British Columbia, Vancouver BC, Canada
  14. 14Huntsman Cancer Institute, University of Utah, Salt Lake City UT, USA
  15. 15University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore MD, USA
  16. 16The University of Oklahoma Health Sciences Center, Oklahoma City OK, USA
  17. 17University of Rochester, Rochester NY, USA
  18. 18University of Wisconsin School of Medicine and Public Health, Madison WI, USAs
  19. 19Stanford Cancer Institute, Palo Alto CA, USA
  20. 20Hospital Maisonneuve-Rosemont, Montreal QC, Canada
  21. 21Children’s Hospital of Los Angeles, Los Angeles CA, USA
  22. 22University of Pennsylvania Abramson Cancer Center, Philadelphia PA, USA
  23. 23Northwestern University, Chicago IL, USA
  24. 24National Cancer Institute, Bethesda MA, USA
  25. 25WVU Cancer Institute at Wheeling Hospital, Wheeling WV, USA
  26. 26Medical College of Wisconsin, Milwaukee WI, USA
  27. 27Washington University School of Medicine, St Louis MO, USA
  28. 28University of California, Irvine, Health Cancer Center-Newport, Orange CA, USA
  29. 29University of Kansas Cancer Center, Westwood KS, USA
  30. 30Mayo Clinic Comprehensive Cancer Center, Rochester MN, USA
  31. 31Yale University, New Haven CT, USA
  32. 32Virginia Commonwealth University Massey Cancer Center, Richmond VA, USA
  33. 33Cleveland Clinic Foundation, Cleveland OH, USA
  34. 34University of California, San Diego, Moores Cancer Center, La Jolla CA, USA
  35. 35University of Alabama at Birmingham, Birmingham AL, USA
  36. 36Duke University Medical Center, Durham NC, USA
  37. 37Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis TN, USA
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Cite

BibTeXRIS
BibTeX
@article{zhong2026genomic,
  title = {{Genomic drivers of leukemia and blinatumomab response in adult acute lymphoblastic leukemia – the ECOG-ACRIN E1910 study}},
  author = {Xiaoming Zhong and Kathryn G. Roberts and Huimei Wei and Zhuoxin Sun and Lindsey E. Montefiori and Amit Kumar and Ilaria Iacobucci and Pradyumna Baviskar and Qingsong Gao and Petri Pölönen and Shondra M. Pruett-Miller and Rori M. Schreiber and Ti-Cheng Chang and Wenchao Zhang and Shaohua Lei and Evadnie Rampersaud and Yiping Fan and Gang Wu and Ryan J. Mattison and Yanming Zhang and Janis Racevskis and Hillard M. Lazarus and Jacob M. Rowe and Daniel A. Arber and Matthew J. Wieduwilt and Yasser A. Mourad and Paul J. Shami and Maria R. Baer and Adam Asch and Kristen M. O’Dwyer and Aric Hall and Michaela Liedtke and Julie Bergeron and Brent L. Wood and Keith W. Pratz and Shira N. Dinner and Noelle Frey and Steven D. Gore and Bhavana Bhatnagar and Ehab L. Atallah and Geoffrey L. Uy and Deepa Jeyakumar and Tara L. Lin and Cheryl L. Willman and Nikolai Podoltsev and Daniel J. DeAngelo and Shejal B. Patel and Michelle A. Elliot and Anjali S. Advani and Dimitrios Tzachanis and Pankit Vachhani and Rupali Roy Bhave and Elad Sharon and Richard F. Little and Harry P. Erba and Richard M. Stone and Martin S. Tallman and Jun J. Yang and Selina M. Luger and Elisabeth M. Paietta},
  journal = {Blood},
  year = {2026},
  month = oct,
  doi = {10.1182/blood.2026033793},
  url = {https://doi.org/10.1182/blood.2026033793},
}
RIS
TY  - JOUR
TI  - Genomic drivers of leukemia and blinatumomab response in adult acute lymphoblastic leukemia – the ECOG-ACRIN E1910 study
AU  - Xiaoming Zhong
AU  - Kathryn G. Roberts
AU  - Huimei Wei
AU  - Zhuoxin Sun
AU  - Lindsey E. Montefiori
AU  - Amit Kumar
AU  - Ilaria Iacobucci
AU  - Pradyumna Baviskar
AU  - Qingsong Gao
AU  - Petri Pölönen
AU  - Shondra M. Pruett-Miller
AU  - Rori M. Schreiber
AU  - Ti-Cheng Chang
AU  - Wenchao Zhang
AU  - Shaohua Lei
AU  - Evadnie Rampersaud
AU  - Yiping Fan
AU  - Gang Wu
AU  - Ryan J. Mattison
AU  - Yanming Zhang
AU  - Janis Racevskis
AU  - Hillard M. Lazarus
AU  - Jacob M. Rowe
AU  - Daniel A. Arber
AU  - Matthew J. Wieduwilt
AU  - Yasser A. Mourad
AU  - Paul J. Shami
AU  - Maria R. Baer
AU  - Adam Asch
AU  - Kristen M. O’Dwyer
AU  - Aric Hall
AU  - Michaela Liedtke
AU  - Julie Bergeron
AU  - Brent L. Wood
AU  - Keith W. Pratz
AU  - Shira N. Dinner
AU  - Noelle Frey
AU  - Steven D. Gore
AU  - Bhavana Bhatnagar
AU  - Ehab L. Atallah
AU  - Geoffrey L. Uy
AU  - Deepa Jeyakumar
AU  - Tara L. Lin
AU  - Cheryl L. Willman
AU  - Nikolai Podoltsev
AU  - Daniel J. DeAngelo
AU  - Shejal B. Patel
AU  - Michelle A. Elliot
AU  - Anjali S. Advani
AU  - Dimitrios Tzachanis
AU  - Pankit Vachhani
AU  - Rupali Roy Bhave
AU  - Elad Sharon
AU  - Richard F. Little
AU  - Harry P. Erba
AU  - Richard M. Stone
AU  - Martin S. Tallman
AU  - Jun J. Yang
AU  - Selina M. Luger
AU  - Elisabeth M. Paietta
PY  - 2026
DA  - 2026/10/05
JO  - Blood
DO  - 10.1182/blood.2026033793
UR  - https://doi.org/10.1182/blood.2026033793
SN  - 0006-4971
SN  - 1528-0020
ER  -