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Peer-reviewedCC BY-NC-NDCurrent Transplantation Reports

A case report of liver transplantation following a biliopancreatic diversion: A friendly cohabitation?

Abstract

Today, bariatric surgery has become the main therapeutic means to fight against the escalating increase in obesity, worldwide. Besides that, non-alcoholic steatohepatitis has inflated its indication for liver transplantation. Liver transplant surgeons are prone to face more and more patients with such background. Here, we described the first case of liver transplantation for hepatocellular carcinoma in a patient with previous history of biliopancreatic diversion with duodenal switch. Biliopancreatic diversion with duodenal switch is nowadays an uncommon bariatric surgery but use to be a second stage surgery following sleeve gastrectomy. Liver transplantation can be challenging as such bariatric procedure reshape the digestive anatomy and can also be responsible for malnutrition. Without such complication and in a center specialized in bariatric surgery and liver transplantation, such cases can be successful and should not alarm liver transplant surgeons. In our case, the bariatric anatomy was conserved, and the liver transplantation was successful, without difficulty of the post-operative immunosuppressive treatment. However, long term follow-up showed an exacerbation of the sarcopenia level and establish even more the need for an association of a well-planned physical and nutritional rehabilitation in the peri-operative period in such candidate.

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BibTeX
@article{frey2026case,
  title = {{A case report of liver transplantation following a biliopancreatic diversion: A friendly cohabitation?}},
  author = {Sébastien Frey and Lidia Santarpia and Madleen Chassang and Anne-Sophie Schneck and Rodolphe Anty and Jean Gugenheim and Antonio Iannelli},
  journal = {Current Transplantation Reports},
  year = {2026},
  month = oct,
  doi = {10.1016/j.tpr.2020.100067},
  url = {https://hal.science/hal-05796727v1},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - A case report of liver transplantation following a biliopancreatic diversion: A friendly cohabitation?
AU  - Sébastien Frey
AU  - Lidia Santarpia
AU  - Madleen Chassang
AU  - Anne-Sophie Schneck
AU  - Rodolphe Anty
AU  - Jean Gugenheim
AU  - Antonio Iannelli
PY  - 2026
DA  - 2026/10/13
JO  - Current Transplantation Reports
DO  - 10.1016/j.tpr.2020.100067
UR  - https://hal.science/hal-05796727v1
AB  - Today, bariatric surgery has become the main therapeutic means to fight against the escalating increase in obesity, worldwide. Besides that, non-alcoholic steatohepatitis has inflated its indication for liver transplantation. Liver transplant surgeons are prone to face more and more patients with such background. Here, we described the first case of liver transplantation for hepatocellular carcinoma in a patient with previous history of biliopancreatic diversion with duodenal switch. Biliopancreatic diversion with duodenal switch is nowadays an uncommon bariatric surgery but use to be a second stage surgery following sleeve gastrectomy. Liver transplantation can be challenging as such bariatric procedure reshape the digestive anatomy and can also be responsible for malnutrition. Without such complication and in a center specialized in bariatric surgery and liver transplantation, such cases can be successful and should not alarm liver transplant surgeons. In our case, the bariatric anatomy was conserved, and the liver transplantation was successful, without difficulty of the post-operative immunosuppressive treatment. However, long term follow-up showed an exacerbation of the sarcopenia level and establish even more the need for an association of a well-planned physical and nutritional rehabilitation in the peri-operative period in such candidate.
SN  - 2196-3029
ER  -