Molecular Insights into Nutrient-Driven Regulation of Trophic Strategies and Life-Cycle Shifts in Bloom-Forming Mixotrophic Dinoflagellates.
- 1Institute of Cytology of the Russian Academy of Sciences, St. Petersburg 194064, Russia.
- 2Institute for Biosciences, Faculty of Mathematics and Natural Sciences, University of Rostock, 18051 Rostock, Germany.
- 3Zoological Institute of the Russian Academy of Sciences, St. Petersburg 199034, Russia.
Abstract
Research into the molecular machinery of eukaryotic unicellular organisms (protists) offers a unique opportunity to unveil the mechanisms of intricate cellular processes and complete life cycles at the level of a single cell operating as a whole organism. Knowledge of protistan molecular biology and life-cycle shifts as adaptations to varying physical-chemical features of the environment helps resolve important issues like evaluation of the balance between external abiotic triggers and internal molecular drivers of cell development. Understanding the molecular mechanisms of these processes is crucial for prognostic modeling of the population growth of ecologically and economically important protists, like toxic species that form harmful algal blooms (HABs) that currently expand worldwide. Here, we review the basic features of bloom-forming mixotrophic dinoflagellates as drivers of their excess proliferation and HABs. We unveil key components of molecular machinery involved in life-cycle regulation of dinoflagellates and highlight the deficiency/redundancy of nitrogen- and phosphorus-containing substrates as modulators of life cycles, diversity and nutrition strategies, including mixotrophy and kleptoplasty. We discuss linkages between cellular and molecular biology, omics and ecological modeling, since merging the research approaches of these disciplines is a promising perspective for future progress of molecular biology within the framework of translational aquatic ecology.
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BibTeX
@article{skarlato2026molecular,
title = {{Molecular Insights into Nutrient-Driven Regulation of Trophic Strategies and Life-Cycle Shifts in Bloom-Forming Mixotrophic Dinoflagellates.}},
author = {Sergei O Skarlato and Mariia A Berdieva and Vera O Kalinina and Hendrik Schubert and Irena V Telesh},
journal = {International journal of molecular sciences},
year = {2026},
month = sep,
doi = {10.3390/ijms27198622},
url = {https://europepmc.org/article/MED/42883868},
note = {CC BY},
}
RIS
TY - JOUR
TI - Molecular Insights into Nutrient-Driven Regulation of Trophic Strategies and Life-Cycle Shifts in Bloom-Forming Mixotrophic Dinoflagellates.
AU - Sergei O Skarlato
AU - Mariia A Berdieva
AU - Vera O Kalinina
AU - Hendrik Schubert
AU - Irena V Telesh
PY - 2026
DA - 2026/09/26
JO - International journal of molecular sciences
DO - 10.3390/ijms27198622
UR - https://europepmc.org/article/MED/42883868
AB - Research into the molecular machinery of eukaryotic unicellular organisms (protists) offers a unique opportunity to unveil the mechanisms of intricate cellular processes and complete life cycles at the level of a single cell operating as a whole organism. Knowledge of protistan molecular biology and life-cycle shifts as adaptations to varying physical-chemical features of the environment helps resolve important issues like evaluation of the balance between external abiotic triggers and internal molecular drivers of cell development. Understanding the molecular mechanisms of these processes is crucial for prognostic modeling of the population growth of ecologically and economically important protists, like toxic species that form harmful algal blooms (HABs) that currently expand worldwide. Here, we review the basic features of bloom-forming mixotrophic dinoflagellates as drivers of their excess proliferation and HABs. We unveil key components of molecular machinery involved in life-cycle regulation of dinoflagellates and highlight the deficiency/redundancy of nitrogen- and phosphorus-containing substrates as modulators of life cycles, diversity and nutrition strategies, including mixotrophy and kleptoplasty. We discuss linkages between cellular and molecular biology, omics and ecological modeling, since merging the research approaches of these disciplines is a promising perspective for future progress of molecular biology within the framework of translational aquatic ecology.
SN - 1422-0067
ER -