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Peer-reviewedCC BY 4.0Journal of Clinical Medicine

Effects of a Multicomponent Exercise Program on Physical Functions and Quality of Life in Pre-Frail and Frail Women: A Randomized Controlled Trial Protocol

  1. 1Department of Health and Rehabilitation Sciences, College of Applied Medical Sciences in Al-Kharj, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia

Abstract

Purpose: The aim of this study is to assess the effect of a multicomponent exercise program versus usual care on physical performance and quality of life in pre-frail and frail community-dwelling women. Methods: A 24-week randomized controlled trial will be conducted on women aged ≥50 years who have pre-frailty or frailty according to the FRAIL scale and are able to walk 10 m without assistance. Recruited participants will be randomized into two groups: the intervention group will receive 24 weeks of multicomponent exercise (12 weeks supervised center-based, then 12 weeks home-based), and the control group will receive their usual care. Physical functions will be measured using Short Physical Performance Battery, Mini Balance Evaluation Systems Test, Activities-Specific Balance Confidence, Falls Efficacy Scale International, Rapid Assessment of Physical Activity, Tilburg frailty instrument, and Barthel Index. Health-related quality of life will be assessed using the Arabic version of SF-12. All outcomes will be measured at baseline and after 12 weeks and 24 weeks of intervention. Discussion: Results from this research will show whether 24 weeks of multicomponent exercise will improve physical performance and quality of life among pre-frail and frail women. The findings will guide healthcare providers to effectively monitor and manage frailty in this population.

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BibTeX
@article{alhwoaimel2026effects,
  title = {{Effects of a Multicomponent Exercise Program on Physical Functions and Quality of Life in Pre-Frail and Frail Women: A Randomized Controlled Trial Protocol}},
  author = {Norah A. Alhwoaimel and Bader A. Alqahtani and Aqeel M. Alenazi},
  journal = {Journal of Clinical Medicine},
  year = {2026},
  month = oct,
  doi = {10.3390/jcm15218331},
  url = {https://www.mdpi.com/2077-0383/15/21/8331},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Effects of a Multicomponent Exercise Program on Physical Functions and Quality of Life in Pre-Frail and Frail Women: A Randomized Controlled Trial Protocol
AU  - Norah A. Alhwoaimel
AU  - Bader A. Alqahtani
AU  - Aqeel M. Alenazi
PY  - 2026
DA  - 2026/10/26
JO  - Journal of Clinical Medicine
DO  - 10.3390/jcm15218331
UR  - https://www.mdpi.com/2077-0383/15/21/8331
AB  - Purpose: The aim of this study is to assess the effect of a multicomponent exercise program versus usual care on physical performance and quality of life in pre-frail and frail community-dwelling women. Methods: A 24-week randomized controlled trial will be conducted on women aged ≥50 years who have pre-frailty or frailty according to the FRAIL scale and are able to walk 10 m without assistance. Recruited participants will be randomized into two groups: the intervention group will receive 24 weeks of multicomponent exercise (12 weeks supervised center-based, then 12 weeks home-based), and the control group will receive their usual care. Physical functions will be measured using Short Physical Performance Battery, Mini Balance Evaluation Systems Test, Activities-Specific Balance Confidence, Falls Efficacy Scale International, Rapid Assessment of Physical Activity, Tilburg frailty instrument, and Barthel Index. Health-related quality of life will be assessed using the Arabic version of SF-12. All outcomes will be measured at baseline and after 12 weeks and 24 weeks of intervention. Discussion: Results from this research will show whether 24 weeks of multicomponent exercise will improve physical performance and quality of life among pre-frail and frail women. The findings will guide healthcare providers to effectively monitor and manage frailty in this population.
SN  - 2077-0383
ER  -