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Peer-reviewedCC BY-NC-ND 4.0BMC Pediatrics

Synchronous B-lymphoblastic leukemia/lymphoma and subcutaneous panniculitis-like T-cell lymphoma in an 11-year-old pediatric patient

4 affiliations
  1. 1Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400 Thailand
  2. 2Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400 Thailand
  3. 3Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, 10400 Thailand
  4. 4Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Samut Prakan, 10540 Thailand

Abstract

Background: Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is rare in pediatric patients, whereas B-lymphoblastic leukemia/lymphoma (B-ALL) is a common childhood hematologic malignancy. The synchronous occurrence of these two distinct lymphoid neoplasms is exceedingly rare, with only two previously reported pediatric cases.

Case presentation: We describe the case of an 11-year-old boy with biopsy-proven SPTCL whose staging marrow examination revealed concurrent B-ALL. The patient was treated according to the B-ALL protocol, and the cutaneous lesions resolved promptly after induction therapy.

Conclusion: This case highlights the importance of comprehensive skin biopsy and staging. Management in such cases should be directed toward the B-ALL component.

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BibTeX
@article{limchantra2026synchronous,
  title = {{Synchronous B-lymphoblastic leukemia/lymphoma and subcutaneous panniculitis-like T-cell lymphoma in an 11-year-old pediatric patient}},
  author = {Phuphinyo Limchantra and Jirat Temsangsukmanee and Suradej Hongeng and Kran Suknuntha},
  journal = {BMC Pediatrics},
  year = {2026},
  month = aug,
  doi = {10.1186/s12887-026-07270-y},
  url = {https://doi.org/10.1186/s12887-026-07270-y},
  note = {CC BY-NC-ND 4.0},
}
RIS
TY  - JOUR
TI  - Synchronous B-lymphoblastic leukemia/lymphoma and subcutaneous panniculitis-like T-cell lymphoma in an 11-year-old pediatric patient
AU  - Phuphinyo Limchantra
AU  - Jirat Temsangsukmanee
AU  - Suradej Hongeng
AU  - Kran Suknuntha
PY  - 2026
DA  - 2026/08/06
JO  - BMC Pediatrics
DO  - 10.1186/s12887-026-07270-y
UR  - https://doi.org/10.1186/s12887-026-07270-y
AB  - Background: Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is rare in pediatric patients, whereas B-lymphoblastic leukemia/lymphoma (B-ALL) is a common childhood hematologic malignancy. The synchronous occurrence of these two distinct lymphoid neoplasms is exceedingly rare, with only two previously reported pediatric cases.  Case presentation: We describe the case of an 11-year-old boy with biopsy-proven SPTCL whose staging marrow examination revealed concurrent B-ALL. The patient was treated according to the B-ALL protocol, and the cutaneous lesions resolved promptly after induction therapy.  Conclusion: This case highlights the importance of comprehensive skin biopsy and staging. Management in such cases should be directed toward the B-ALL component.
SN  - 1471-2431
ER  -