Peer-reviewedCC BYThe Journal of clinical investigation
Interferon-λ inhibits immunopathology and boosts T cell–mediated immunity in a mouse model of mucosal viral infection
4 affiliations
- 1McMaster Immunology Research Centre, Department of Medicine and
- 2University Hospital Regensburg, Department of Nephrology, Regensburg, Germany.
- 3Department of Microbiology, Biochemistry, and Molecular Genetics, Rutgers New Jersey Medical School, Newark, New Jersey, USA.
- 4Department of Immunology, University of Manitoba, Winnipeg, Manitoba, Canada.
Related
- Convergent Immunopathology in Influenza-Associated Encephalopathy: CD3+ CD4+ T Cell Depletion, IL-6-Mediated Inflammation, and Complement C3 Dysregulation
- Corticosteroids drive oral candidiasis by impairing type-17 immunity without inducing interferon-gammopathy
- A HiBiT-Tagged influenza A virus reporter system reveals cytokine-inhibitory micropeptide 53 as a modulator of viral infection and immunopathology
- Early dynamics of a neutrophil interferon program drive immunotherapy resistance and limit durable anti-tumor immunity
- Placental immunopathology and congenital transmission of Zika virus and Trypanosoma cruzi: comparative mechanisms, immune disturbances, and potential co-infection scenarios
BibTeX
@article{feng2026interferonλ,
title = {{Interferon-λ inhibits immunopathology and boosts T cell–mediated immunity in a mouse model of mucosal viral infection}},
author = {Emily Feng and Alexa Mansour and Elizabeth Balint and Alyssa Mark and Sofia Tramonte and Jonathan K. Monteiro and Madison Read and Marie Joe Adaimy and Zhou Xing and Matthias Mack and Sergei V. Kotenko and Deanna M. Santer and Ali A. Ashkar},
journal = {The Journal of clinical investigation},
year = {2026},
month = oct,
url = {https://europepmc.org/article/PMC/PMC13668623},
note = {CC BY},
}
RIS
TY - JOUR
TI - Interferon-λ inhibits immunopathology and boosts T cell–mediated immunity in a mouse model of mucosal viral infection
AU - Emily Feng
AU - Alexa Mansour
AU - Elizabeth Balint
AU - Alyssa Mark
AU - Sofia Tramonte
AU - Jonathan K. Monteiro
AU - Madison Read
AU - Marie Joe Adaimy
AU - Zhou Xing
AU - Matthias Mack
AU - Sergei V. Kotenko
AU - Deanna M. Santer
AU - Ali A. Ashkar
PY - 2026
DA - 2026/10/19
JO - The Journal of clinical investigation
UR - https://europepmc.org/article/PMC/PMC13668623
SN - 0021-9738
SN - 1558-8238
ER -