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Peer-reviewedCC BY-NC-NDJournal of healthcare informatics research

A Knowledge Graph Framework for Linking Health Assessment Scales and Scientific Literature in Low-Annotation Settings: Development and Evaluation Study

  1. 1Beijing, China

Abstract

Health assessment scales are essential to measurement-based care, yet their adoption is hindered by difficulties in accessing relevant knowledge dispersed across unstructured scientific literature. This study explores a knowledge graph (KG) approach for the structured representation and semantic integration of health assessment scales and their associated literature metadata, aiming to propose a simple yet effective framework for this task. We defined a fine-grained KG schema that incorporates scale component entities and their relations, cross-scale mappings, and contextual associations. A construction pipeline was developed that combines prompt-based extraction of scale components and relations, type-specific entity normalization and relation fusion, cross-scale semantic mapping, and contextual linkage. To evaluate the pipeline, we built a prototype KG from 55 scales and 234 scientific articles, supported by a manually annotated dataset for cross-sentence relation extraction. Experiments with GLM-4-plus achieved F1 scores of 64.90% and 65.81% for component entity and relation extraction, respectively. Normalization yielded ARI and FMI scores above 0.54 for AssessmentScales and above 0.63 for MeasurementConcepts. Cross-scale mapping achieved F1 scores of 0.80 for AssessmentScales, 0.77 for MeasurementConcepts, and 0.85 for Items. The resulting prototype KG contains 6,468 concept-level entities and 32,096 triples, accessible through a public web interface. The scale-specific KG framework represents a practical method for structuring scale-related knowledge under low-annotation conditions, broadening medical KG research and supporting the advancement of measurement-based care.

Supplementary Information: The online version contains supplementary material available at https://doi.org/10.1007/s41666-026-00247-7.

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BibTeX
@article{sun2026knowledge,
  title = {{A Knowledge Graph Framework for Linking Health Assessment Scales and Scientific Literature in Low-Annotation Settings: Development and Evaluation Study}},
  author = {Haixia Sun and Liang Zhao and Zhenli Chen and Jiao Li and Junlian Li and Jie Hao and Yan Lin and Qing Qian},
  journal = {Journal of healthcare informatics research},
  year = {2026},
  month = jul,
  doi = {10.1007/s41666-026-00247-7},
  url = {https://europepmc.org/article/PMC/PMC13719916},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - A Knowledge Graph Framework for Linking Health Assessment Scales and Scientific Literature in Low-Annotation Settings: Development and Evaluation Study
AU  - Haixia Sun
AU  - Liang Zhao
AU  - Zhenli Chen
AU  - Jiao Li
AU  - Junlian Li
AU  - Jie Hao
AU  - Yan Lin
AU  - Qing Qian
PY  - 2026
DA  - 2026/07/29
JO  - Journal of healthcare informatics research
DO  - 10.1007/s41666-026-00247-7
UR  - https://europepmc.org/article/PMC/PMC13719916
AB  - Health assessment scales are essential to measurement-based care, yet their adoption is hindered by difficulties in accessing relevant knowledge dispersed across unstructured scientific literature. This study explores a knowledge graph (KG) approach for the structured representation and semantic integration of health assessment scales and their associated literature metadata, aiming to propose a simple yet effective framework for this task. We defined a fine-grained KG schema that incorporates scale component entities and their relations, cross-scale mappings, and contextual associations. A construction pipeline was developed that combines prompt-based extraction of scale components and relations, type-specific entity normalization and relation fusion, cross-scale semantic mapping, and contextual linkage. To evaluate the pipeline, we built a prototype KG from 55 scales and 234 scientific articles, supported by a manually annotated dataset for cross-sentence relation extraction. Experiments with GLM-4-plus achieved F1 scores of 64.90% and 65.81% for component entity and relation extraction, respectively. Normalization yielded ARI and FMI scores above 0.54 for AssessmentScales and above 0.63 for MeasurementConcepts. Cross-scale mapping achieved F1 scores of 0.80 for AssessmentScales, 0.77 for MeasurementConcepts, and 0.85 for Items. The resulting prototype KG contains 6,468 concept-level entities and 32,096 triples, accessible through a public web interface. The scale-specific KG framework represents a practical method for structuring scale-related knowledge under low-annotation conditions, broadening medical KG research and supporting the advancement of measurement-based care.  Supplementary Information: The online version contains supplementary material available at https://doi.org/10.1007/s41666-026-00247-7.
SN  - 2509-4971
SN  - 2509-498X
ER  -