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Peer-reviewedCC BY-NC-NDBMC psychiatry

Prevalence of frailty and associated factors among aging residents with chronic schizophrenia in Taiwanese psychiatric nursing home: a cross-sectional study.

4 affiliations
  1. 1Department of Family Physician and Geriatrician, Mennonite Christian Hospital, Hualien, Taiwan, R.O.C.
  2. 2Department of Nursing, College of Nursing, Tzu Chi University, 880 Chien-Kuo Rd., Sec. 2, , Hualien, 970, Taiwan R.O.C.. [email protected].
  3. 3Gangkou Elementary School, Fengbin Township, Hualien County, Taiwan R.O.C.
  4. 4Department of Nursing, Yuli Hospital, Ministry of Health and Welfare, Yuli, Hualien, Taiwan R.O.C.

Abstract

Background

Frailty is a critical geriatric syndrome reflecting health vulnerability, yet research among residents with chronic schizophrenia remains limited. This study investigated the prevalence and associated factors of frailty in a psychiatric nursing home.Methods

A cross-sectional survey was conducted with 155 participants from a psychiatric nursing home. Assessment tools included the Frailty Scale, BSRS-5, PANSS, and Barthel Index (ADL/IADL). Data were analyzed using t-tests, Pearson correlation, and multivariable logistic regression.Results

The prevalence of frailty was 55.5% (86/155). Multivariable logistic regression revealed that female gender (Model 1: adjusted OR = 4.39, 95% CI = 1.92-10.04; Model 2: adjusted OR = 4.33, 95% CI = 1.90-9.85; both p < 0.001) and higher psychological distress (BSRS scores; Model 1: adjusted OR = 1.94, 95% CI = 1.35-2.79; Model 2: adjusted OR = 2.01, 95% CI = 1.42-2.85; both p < 0.001) were significant independent associated with of increased frailty odds. Although the frail group exhibited significantly more severe psychiatric symptoms across all PANSS subscales (all p < 0.01), no significant differences were found in ADL or IADL scores between the two groups.Conclusions

These findings suggest that frailty represents a multidimensional vulnerability that co-occurs with psychiatric symptoms alongside preserved functional independence. Routine integration of frailty screening into psychiatric assessments is recommended to inform interdisciplinary care strategies.Clinical trial number

Not applicable.

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BibTeX
@article{liu2026prevalence,
  title = {{Prevalence of frailty and associated factors among aging residents with chronic schizophrenia in Taiwanese psychiatric nursing home: a cross-sectional study.}},
  author = {Tse-Tsung Liu and Su-Jung Liao and Chia-Jou Hsieh},
  journal = {BMC psychiatry},
  year = {2026},
  month = oct,
  doi = {10.1186/s12888-026-08746-y},
  url = {https://europepmc.org/article/MED/42972345},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Prevalence of frailty and associated factors among aging residents with chronic schizophrenia in Taiwanese psychiatric nursing home: a cross-sectional study.
AU  - Tse-Tsung Liu
AU  - Su-Jung Liao
AU  - Chia-Jou Hsieh
PY  - 2026
DA  - 2026/10/09
JO  - BMC psychiatry
DO  - 10.1186/s12888-026-08746-y
UR  - https://europepmc.org/article/MED/42972345
AB  - Background  Frailty is a critical geriatric syndrome reflecting health vulnerability, yet research among residents with chronic schizophrenia remains limited. This study investigated the prevalence and associated factors of frailty in a psychiatric nursing home.Methods  A cross-sectional survey was conducted with 155 participants from a psychiatric nursing home. Assessment tools included the Frailty Scale, BSRS-5, PANSS, and Barthel Index (ADL/IADL). Data were analyzed using t-tests, Pearson correlation, and multivariable logistic regression.Results  The prevalence of frailty was 55.5% (86/155). Multivariable logistic regression revealed that female gender (Model 1: adjusted OR = 4.39, 95% CI = 1.92-10.04; Model 2: adjusted OR = 4.33, 95% CI = 1.90-9.85; both p < 0.001) and higher psychological distress (BSRS scores; Model 1: adjusted OR = 1.94, 95% CI = 1.35-2.79; Model 2: adjusted OR = 2.01, 95% CI = 1.42-2.85; both p < 0.001) were significant independent associated with of increased frailty odds. Although the frail group exhibited significantly more severe psychiatric symptoms across all PANSS subscales (all p < 0.01), no significant differences were found in ADL or IADL scores between the two groups.Conclusions  These findings suggest that frailty represents a multidimensional vulnerability that co-occurs with psychiatric symptoms alongside preserved functional independence. Routine integration of frailty screening into psychiatric assessments is recommended to inform interdisciplinary care strategies.Clinical trial number  Not applicable.
SN  - 1471-244X
ER  -