Peer-reviewedLicence not statedCancer immunology research3 Nov 2026

Cancer Immunotherapy Using AIRE Conditioning of the Tumor Epitopeome

Alex Chen¹
Jose S. Pulido^1,2
Jason Tonne¹
Muriel Metko¹
Jill M. Thompson¹
Thanich Sangsuwannukul¹
Maria P. Chiriboga Yerovi¹
Rosa M. Diaz¹
Mason J. Webb¹
Amanda L. Huff¹
Madelyn Moore^1,3
Matthew R. Schuelke¹

5 more authors

Sheeba Irshad⁴
Elizabeth Appleton⁵
Alan Melcher⁵
Benjamin Kendall¹
Richard G. Vile^1,4,6,7

7 affiliations

¹Department of Molecular Medicine, Mayo Clinic; Rochester, MN, USA.
²Wills Eye Hospital and Thomas Jefferson University; Philadelphia, PA, USA.
³Department of Pharmacology, University of Minnesota; Minneapolis, MN, USA.
⁴Comprehensive Cancer Centre, School of Cancer & Pharmaceutical Sciences, King’s College London, London, UK, Breast Cancer Now Research Unit, King’s College London, London, UK; Guy’s and St Thomas’ NHS Foundation Trust.
⁵The Institute of Cancer Research, Division of Radiotherapy and Imaging, Chester Beatty Laboratories; London, UK.
⁶Joan Reece Professor of Immuno-oncology, Comprehensive Cancer Centre, School of Cancer & Pharmaceutical Sciences, School of Immunology and Microbial Sciences, King’s College London, UK.
⁷Department of Immunology, Mayo Clinic; Rochester, MN, USA.

Read full text DOI Cite

Exploring tumor-derived exosomes as promising antigenic platforms: novel vaccine and immunotherapy strategies for “cold” colorectal cancer
Xiaoting Liu, Xiaoyan Wang
Frontiers in immunology16 Oct 2026Peer-reviewedCC BYFull textImmunologyEurope PMC
Editorial: The differentiation and reprogramming of tumor-associated myeloid cells and therapeutic strategies for cancer immunotherapy
Paul Takam Kamga, Lionel Franz Poulin, Li Lily Wang
Frontiers in Immunology16 Oct 2026Peer-reviewedCC BY 4.0Full textImmunologyCrossrefHAL
Precision targeting of tumor-associated macrophages via a 6-substituted pyrrolo[2,3-d]pyrimidine chimeric molecule for enhanced cancer immunotherapy
Yining Zhang, Binghao Guo, Lixiao Guo +16
Communications Chemistry15 Oct 2026Peer-reviewedCC BY-NC-ND 4.0Full textImmunologyCrossref
Targeting Dendritic Cells in Cancer Immunotherapy: From Immune Priming to Tumor Microenvironment Reprogramming
Serena Zanotta, Domenico Galati
International Journal of Molecular Sciences27 Oct 2026Peer-reviewedCC BY 4.0ImmunologyCrossref
Molecular Checkpoints of Nucleic Acid Sensing in Tumor Cells: Linking Innate Immune Evasion to Precision Cancer Immunotherapy
Yan Wang, Bowei Cao, Huili Lu +2
International Journal of Molecular Sciences22 Oct 2026Peer-reviewedCC BY 4.0ImmunologyCrossref

Cite

BibTeX RIS

BibTeX

@article{chen2026cancer,
  title = {{Cancer Immunotherapy Using AIRE Conditioning of the Tumor Epitopeome}},
  author = {Alex Chen and Jose S. Pulido and Jason Tonne and Muriel Metko and Jill M. Thompson and Thanich Sangsuwannukul and Maria P. Chiriboga Yerovi and Rosa M. Diaz and Mason J. Webb and Amanda L. Huff and Madelyn Moore and Matthew R. Schuelke and Sheeba Irshad and Elizabeth Appleton and Alan Melcher and Benjamin Kendall and Richard G. Vile},
  journal = {Cancer immunology research},
  year = {2026},
  month = nov,
  doi = {10.1158/2326-6066.cir-25-1589},
  url = {https://doi.org/10.1158/2326-6066.cir-25-1589},
}

RIS

TY  - JOUR
TI  - Cancer Immunotherapy Using AIRE Conditioning of the Tumor Epitopeome
AU  - Alex Chen
AU  - Jose S. Pulido
AU  - Jason Tonne
AU  - Muriel Metko
AU  - Jill M. Thompson
AU  - Thanich Sangsuwannukul
AU  - Maria P. Chiriboga Yerovi
AU  - Rosa M. Diaz
AU  - Mason J. Webb
AU  - Amanda L. Huff
AU  - Madelyn Moore
AU  - Matthew R. Schuelke
AU  - Sheeba Irshad
AU  - Elizabeth Appleton
AU  - Alan Melcher
AU  - Benjamin Kendall
AU  - Richard G. Vile
PY  - 2026
DA  - 2026/11/03
JO  - Cancer immunology research
DO  - 10.1158/2326-6066.cir-25-1589
UR  - https://doi.org/10.1158/2326-6066.cir-25-1589
SN  - 2326-6066
SN  - 2326-6074
ER  -

Related

Cite