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Peer-reviewedCC BYCase reports in dermatological medicine

Lymphangioma Circumscriptum-Like Cutaneous Manifestation in Metastatic Colorectal Cancer: A Case Report Highlighting the Role of Dermatology in the Detection of Systemic Disease Progression.

  1. 1Asad Al-Hamad Dermatology Center Al Sabah Hospital Kuwait City Kuwait.
  2. 2Jaber Al Ahmed Al Jaber Al Sabah Hospital Surra Al Asimah Governorate Kuwait.

Abstract

Cutaneous metastases may rarely present as translucent vesicular lesions resembling lymphangioma circumscriptum (LC), posing a significant diagnostic challenge. Although colorectal cancer is among the most common malignancies globally, cutaneous metastasis remains uncommon. We present a case of a 40-year-old man with metastatic colorectal signet-ring cell adenocarcinoma who presented with grouped translucent vesicles on the left lateral neck. Immunohistopathologic evaluation supported metastatic cutaneous involvement of the colorectal adenocarcinoma. This case highlights the prognostic significance of recognizing atypical cutaneous metastases and underscores the role of dermatologists in identifying disease progression through timely skin biopsy and clinicopathologic correlation. In addition, a review of previously reported solid-tumor-associated LC-like metastases places this presentation within the broader spectrum of metastatic cutaneous disease.

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BibTeX
@article{alghaith2026lymphangioma,
  title = {{Lymphangioma Circumscriptum-Like Cutaneous Manifestation in Metastatic Colorectal Cancer: A Case Report Highlighting the Role of Dermatology in the Detection of Systemic Disease Progression.}},
  author = {F A Alghaith and R Harby and F AlJaber and R Etman and H Al-Sabah and A AlLafi},
  journal = {Case reports in dermatological medicine},
  year = {2026},
  month = oct,
  doi = {10.1155/crdm/5173964},
  url = {https://europepmc.org/article/MED/42909875},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Lymphangioma Circumscriptum-Like Cutaneous Manifestation in Metastatic Colorectal Cancer: A Case Report Highlighting the Role of Dermatology in the Detection of Systemic Disease Progression.
AU  - F A Alghaith
AU  - R Harby
AU  - F AlJaber
AU  - R Etman
AU  - H Al-Sabah
AU  - A AlLafi
PY  - 2026
DA  - 2026/10/21
JO  - Case reports in dermatological medicine
DO  - 10.1155/crdm/5173964
UR  - https://europepmc.org/article/MED/42909875
AB  - Cutaneous metastases may rarely present as translucent vesicular lesions resembling lymphangioma circumscriptum (LC), posing a significant diagnostic challenge. Although colorectal cancer is among the most common malignancies globally, cutaneous metastasis remains uncommon. We present a case of a 40-year-old man with metastatic colorectal signet-ring cell adenocarcinoma who presented with grouped translucent vesicles on the left lateral neck. Immunohistopathologic evaluation supported metastatic cutaneous involvement of the colorectal adenocarcinoma. This case highlights the prognostic significance of recognizing atypical cutaneous metastases and underscores the role of dermatologists in identifying disease progression through timely skin biopsy and clinicopathologic correlation. In addition, a review of previously reported solid-tumor-associated LC-like metastases places this presentation within the broader spectrum of metastatic cutaneous disease.
SN  - 2090-6463
SN  - 2090-6471
ER  -