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PreprintCC BY-NCbioRxiv

Specific basal ganglia, amygdala, and cortical neurons are associated with borderline personality disorder (BPD)

  • H. Senturk
  • H. Segal-Gavish
  • J. Tucciarone
  • L. Duncan1
  1. 1Stanford University, Department of Psychiatry and Behavioral Sciences, Stanford, CA 94305; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94
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Abstract

Borderline personality disorder (BPD) is clinically significant and poorly understood biologically. We tested which human brain cell types preferentially use genes associated with BPD, implicating two major types of neurons: LAMP5 interneurons and D2 medium spiny neurons. These interrogable cell types provide new avenues for investigating the neurobiology of BPD.

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Cite

BibTeXRIS
BibTeX
@misc{senturk2026specific,
  title = {{Specific basal ganglia, amygdala, and cortical neurons are associated with borderline personality disorder (BPD)}},
  author = {H. Senturk and H. Segal-Gavish and J. Tucciarone and L. Duncan},
  howpublished = {bioRxiv},
  year = {2026},
  month = sep,
  doi = {10.64898/2026.09.04.749244},
  url = {https://www.biorxiv.org/content/10.64898/2026.09.04.749244v1},
  note = {CC BY-NC},
}
RIS
TY  - UNPB
TI  - Specific basal ganglia, amygdala, and cortical neurons are associated with borderline personality disorder (BPD)
AU  - H. Senturk
AU  - H. Segal-Gavish
AU  - J. Tucciarone
AU  - L. Duncan
PY  - 2026
DA  - 2026/09/04
PB  - bioRxiv
DO  - 10.64898/2026.09.04.749244
UR  - https://www.biorxiv.org/content/10.64898/2026.09.04.749244v1
AB  - Borderline personality disorder (BPD) is clinically significant and poorly understood biologically. We tested which human brain cell types preferentially use genes associated with BPD, implicating two major types of neurons: LAMP5 interneurons and D2 medium spiny neurons. These interrogable cell types provide new avenues for investigating the neurobiology of BPD.
ER  -