Pathophysiology, workup and treatment of cancer-related ischaemic stroke

Abstract

Cancer and acute ischaemic stroke are two leading causes of mortality worldwide. The association between these two diseases is being increasingly recognised, and with improvements in cancer mortality, the co-prevalence is increasing. Evidence suggested that cancer-related ischaemic stroke is a unique subtype of stroke, including a newly proposed schematic to define this subgroup of patients. Cancer-related ischaemic stroke encompasses a heterogeneous group of mechanisms that requires individualised diagnostic evaluation and multidisciplinary collaboration. In this narrative review, we describe the pathophysiology, workup, and management considerations in patients with cancer and ischaemic stroke.

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BibTeX RIS

BibTeX

@article{patel2026pathophysiology,
  title = {{Pathophysiology, workup and treatment of cancer-related ischaemic stroke}},
  author = {Shivam Patel and Soma Sengupta and Wuwei Feng and Dylan Ryan},
  journal = {Clinical medicine (London, England)},
  year = {2026},
  month = sep,
  doi = {10.1016/j.clinme.2026.100656},
  url = {https://europepmc.org/article/PMC/PMC13730225},
  note = {CC BY-NC-ND},
}

RIS

TY  - JOUR
TI  - Pathophysiology, workup and treatment of cancer-related ischaemic stroke
AU  - Shivam Patel
AU  - Soma Sengupta
AU  - Wuwei Feng
AU  - Dylan Ryan
PY  - 2026
DA  - 2026/09/01
JO  - Clinical medicine (London, England)
DO  - 10.1016/j.clinme.2026.100656
UR  - https://europepmc.org/article/PMC/PMC13730225
AB  - Cancer and acute ischaemic stroke are two leading causes of mortality worldwide. The association between these two diseases is being increasingly recognised, and with improvements in cancer mortality, the co-prevalence is increasing. Evidence suggested that cancer-related ischaemic stroke is a unique subtype of stroke, including a newly proposed schematic to define this subgroup of patients. Cancer-related ischaemic stroke encompasses a heterogeneous group of mechanisms that requires individualised diagnostic evaluation and multidisciplinary collaboration. In this narrative review, we describe the pathophysiology, workup, and management considerations in patients with cancer and ischaemic stroke.
SN  - 1470-2118
SN  - 1473-4893
ER  -

Abstract

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