A Convenient Crystalline Acyl Silane for the Colorimetric Titration of Diisobutylaluminum Hydride (DIBAL)
- 1Department of Chemistry, Virginia Commonwealth University, 1001 West Main Street, Richmond, VA
Abstract
Due to the intense color associated with acyl silanes and their fast reaction with DIBAL to generate colorless alcohols, these properties were utilized to develop a colorimetric titration of DIBAL. A convenient crystalline acyl silane was identified that can be prepared on gram scale without the need for chromatographic purification by direct crystallization of the reaction products. Use of this material for the colorimetric titration of DIBAL and n-BuLi was possible. A variety of other 2 hydride and organometallic reagents were also tested and showed unsatisfactory endpoints. This work was performed by an American Chemical Society Project SEED student during their summer fellowship under the direction of a senior graduate student. The work disclosed could be suitable for application to an advanced undergraduate level laboratory related to the titration of reactive hydride reagents including the significance of atom effects on the physical and chemical properties or organic compounds.
Related
- Clickable Photolabile Linkers for Convenient Immobilization and Light-Controlled Release of Substrates from Solid Support.
- Intramolecular Hydride Migration Enables Ring Substitution in a Diphosphacyclobutadienyl Complex
- A Silica-Supported Tungsten-Iridium Hydride Catalyst with Enhanced Arene H/D Exchange performances
- Hydride formation and interfacial enthalpies between hydrogen and Mg mixtures with immiscible elements/alloys
- Photocluster catalytic oxidation enabled by structurally precise copper-hydride nanoclusters
BibTeX
@misc{collins2026convenient,
title = {{A Convenient Crystalline Acyl Silane for the Colorimetric Titration of Diisobutylaluminum Hydride (DIBAL)}},
author = {Stephen Collins and Colby Basnett and Joshua D. Sieber},
howpublished = {ChemRxiv},
year = {2026},
month = sep,
doi = {10.26434/chemrxiv.15009371/v1},
url = {https://chemrxiv.org/doi/full/10.26434/chemrxiv.15009371/v1},
note = {CC BY},
}
RIS
TY - UNPB
TI - A Convenient Crystalline Acyl Silane for the Colorimetric Titration of Diisobutylaluminum Hydride (DIBAL)
AU - Stephen Collins
AU - Colby Basnett
AU - Joshua D. Sieber
PY - 2026
DA - 2026/09/23
PB - ChemRxiv
DO - 10.26434/chemrxiv.15009371/v1
UR - https://chemrxiv.org/doi/full/10.26434/chemrxiv.15009371/v1
AB - Due to the intense color associated with acyl silanes and their fast reaction with DIBAL to generate colorless alcohols, these properties were utilized to develop a colorimetric titration of DIBAL. A convenient crystalline acyl silane was identified that can be prepared on gram scale without the need for chromatographic purification by direct crystallization of the reaction products. Use of this material for the colorimetric titration of DIBAL and n-BuLi was possible. A variety of other 2 hydride and organometallic reagents were also tested and showed unsatisfactory endpoints. This work was performed by an American Chemical Society Project SEED student during their summer fellowship under the direction of a senior graduate student. The work disclosed could be suitable for application to an advanced undergraduate level laboratory related to the titration of reactive hydride reagents including the significance of atom effects on the physical and chemical properties or organic compounds.
ER -