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Peer-reviewedCC BYBrain and behavior

Evidence Mapping, Certainty Appraisal, and Acupoint Prescription Pattern Mining of Acupuncture for Poststroke Dysphagia: An Overview of Systematic Reviews.

4 affiliations
  1. 1Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.
  2. 2Department of Acupuncture, The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.
  3. 3Rehabilitation Center, The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.
  4. 4Heilongjiang Provincial Key Laboratory of Brain Function and Neurorehabilitation, The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.

Abstract

Background

To characterize the methodological quality, certainty of evidence, primary-study overlap, outcome coverage, and recurrent acupuncture prescription patterns in the existing secondary evidence on acupuncture for poststroke dysphagia (PSD).Method

Systematic reviews and meta-analyses (SRs/MAs) evaluating acupuncture for PSD were identified. Methodological quality was assessed using A Measurement Tool to Assess Systematic Reviews 2 (AMSTAR 2), certainty of evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach, and primary-study overlap using the corrected covered area (CCA). Evidence mapping summarized outcome coverage and certainty, and prescription pattern mining explored frequently used acupoints and combinations.Result

Forty-five SRs/MAs were included. Under the original AMSTAR 2 critical-domain configuration, one review was rated moderate, eight low, and 36 critically low. GRADE indicated that most outcome evidence was of low or very low certainty. The CCA was 0.34%, indicating slight overlap of primary studies across reviews. Evidence was concentrated on total effective rate and swallowing-function outcomes, whereas patient-important outcomes, including aspiration/pneumonia, nutritional status, safety, and quality of life, were underrepresented. Frequently used acupoints included Fengchi (GB20), Lianquan (RN23), Jinjin (EX-HN12), and Yuye (EX-HN13), with recurrent combinations reflecting local stimulation and swallowing-related functional regulation.Conclusion

Current secondary evidence suggests that acupuncture, primarily as an adjunctive intervention, may improve swallowing-related outcomes in PSD, but confidence remains limited by methodological weaknesses and low certainty of evidence. Future studies should improve methodological rigor, standardize clinically important outcomes, and prospectively validate recurrent prescription patterns.

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BibTeX
@article{lan2026evidence,
  title = {{Evidence Mapping, Certainty Appraisal, and Acupoint Prescription Pattern Mining of Acupuncture for Poststroke Dysphagia: An Overview of Systematic Reviews.}},
  author = {Guohao Lan and Minmin Wu and Jiongliang Zhang and Yuxuan Li and Yuting Wang and Yumeng Su and Zhiliang Dong and Xiangyu Wei and Luwen Zhu},
  journal = {Brain and behavior},
  year = {2026},
  month = nov,
  doi = {10.1002/brb3.71887},
  url = {https://europepmc.org/article/MED/42967503},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Evidence Mapping, Certainty Appraisal, and Acupoint Prescription Pattern Mining of Acupuncture for Poststroke Dysphagia: An Overview of Systematic Reviews.
AU  - Guohao Lan
AU  - Minmin Wu
AU  - Jiongliang Zhang
AU  - Yuxuan Li
AU  - Yuting Wang
AU  - Yumeng Su
AU  - Zhiliang Dong
AU  - Xiangyu Wei
AU  - Luwen Zhu
PY  - 2026
DA  - 2026/11/01
JO  - Brain and behavior
DO  - 10.1002/brb3.71887
UR  - https://europepmc.org/article/MED/42967503
AB  - Background  To characterize the methodological quality, certainty of evidence, primary-study overlap, outcome coverage, and recurrent acupuncture prescription patterns in the existing secondary evidence on acupuncture for poststroke dysphagia (PSD).Method  Systematic reviews and meta-analyses (SRs/MAs) evaluating acupuncture for PSD were identified. Methodological quality was assessed using A Measurement Tool to Assess Systematic Reviews 2 (AMSTAR 2), certainty of evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach, and primary-study overlap using the corrected covered area (CCA). Evidence mapping summarized outcome coverage and certainty, and prescription pattern mining explored frequently used acupoints and combinations.Result  Forty-five SRs/MAs were included. Under the original AMSTAR 2 critical-domain configuration, one review was rated moderate, eight low, and 36 critically low. GRADE indicated that most outcome evidence was of low or very low certainty. The CCA was 0.34%, indicating slight overlap of primary studies across reviews. Evidence was concentrated on total effective rate and swallowing-function outcomes, whereas patient-important outcomes, including aspiration/pneumonia, nutritional status, safety, and quality of life, were underrepresented. Frequently used acupoints included Fengchi (GB20), Lianquan (RN23), Jinjin (EX-HN12), and Yuye (EX-HN13), with recurrent combinations reflecting local stimulation and swallowing-related functional regulation.Conclusion  Current secondary evidence suggests that acupuncture, primarily as an adjunctive intervention, may improve swallowing-related outcomes in PSD, but confidence remains limited by methodological weaknesses and low certainty of evidence. Future studies should improve methodological rigor, standardize clinically important outcomes, and prospectively validate recurrent prescription patterns.
SN  - 2162-3279
ER  -